Publications by authors named "Vatthanaphone Latthaphasavang"
Background: Laos is considered highly endemic for persistent infection with hepatitis B virus (HBV). To eliminate this burden, it has gradually implemented universal anti-hepatitis B immunisation of newborns over the past two decades.
Methods: Using VIKIA® HBsAg, a rapid test for the qualitative detection of the HBV surface antigen, we conducted between Sep 1st, 2020 and Aug 31st, 2021 the largest prospective prevalence survey ever in Laos.
Article Synopsis
- The study examined the transmission of hepatitis B virus (HBV) from mothers to their infants in Vientiane, Lao PDR, focusing on immunization success rates without the use of hepatitis B immune globulin (HBIg).
- Among 120 infants, only 4% tested positive for HBsAg, all linked to mothers with high viral loads, suggesting lower transmission rates than anticipated.
- The findings indicate that enhancing immunization strategies, potentially by including HBIg and maternal antiviral treatment, could further reduce mother-to-child transmission and improve antibody responses in infants.
The Lao People's Democratic Republic (PDR) is still considered a highly endemic country for hepatitis B, mainly due to perinatal transmission of hepatitis B virus (HBV), despite efforts made since 2004 for universal immunization of newborns. The prevalence of HBV surface antigen (HBsAg) carriage in pregnant women is a relevant marker for the risk of mother-to-child HBV transmission. This study aimed to assess the changes in prevalence of HBV infection among pregnant women attending the Mahosot Prenatal Clinic (Vientiane Capital).
View Article and Find Full Text PDFHealth care workers (HCW) are a population at high risk of hepatitis B virus (HBV) infection, especially in endemic countries such as Lao PDR. Effective vaccines are available since over 10 years, but many HCWs are not aware of the risk of infection and are still not immunized against hepatitis B. This study aimed to assess immunization coverage against hepatitis B among the students of the University of Health Sciences (UHS) of Lao PDR in 2013 and to look for the causes of non-vaccination.
View Article and Find Full Text PDFBackground: Cervical cancer is the first female cancer in Lao PDR, a low-income country with no national screening and prevention programs for this human papillomavirus (HPV) associated pathology. HIV-infected women have a higher risk of persistent oncogenic HPV infection.The purpose of this study was to determine the knowledge, awareness and attitudes about cervical cancer among Lao women attending or not an HIV treatment center, in order to understand if this attendance had offered an opportunity for information and prevention.
View Article and Find Full Text PDFAntiretroviral therapy initiation in France: adherence to national guidelines and outcome.
J Int Assoc Physicians AIDS Care (Chic)
February 2014
Objectives And Methods: Retrospective study of all patients who started antiretroviral therapy (ART) in 2007 in a single center in Paris, with baseline characteristics and 1-year outcome, to assess adherence to national guidelines.
Results: We analyzed 118 patients. Time of ART initiation was in agreement with the guidelines for only 64 (54.