Aim And Objectives: Dental caries is currently considered an ecological imbalance within the oral biofilm leading to the dissolution of the tooth's hard tissues. It has been traditionally thought that two species belonging to the group, (SM) and (SS), are the etiologically responsible for the onset of dental decay.
Materials And Methods: The present study was conducted on 40 children with caries-active (CA) and caries-free (CF).
Aim: The main objective of the present study was to estimate the production of hydrogen peroxide present in saliva and correlate it to early childhood caries using high-performance liquid chromatography [HPLC] method.
Design: The study was conducted on children aged 3-6 years with a sample size of 20 who had decayed, missing, or filled teeth in accordance to WHO pro forma and were divided into two groups: Study group: Caries active [CA][ = 10] and Control group caries free [CF] [ = 10]. The whole saliva was collected into the vials with a buffer solution and was stored in cold storage.