Publications by authors named "Vasyl V. Kishchuk"
Article Synopsis
- Scleroma, caused by Klebsiella pneumoniae, is a rare chronic disease affecting the upper respiratory tract, with unclear causes and numerous immune system disturbances.
- A study analyzed the local immunity in the oropharynx of 92 scleroma patients and 20 healthy individuals, measuring several immune factors in their oropharyngeal secretions.
- The results showed significant decreases in secretory and monomeric immunoglobulins in scleroma patients, indicating a deficiency in local immunity that may contribute to the chronic inflammation seen in the disease, suggesting a need for immune therapy in treatment.
Objective: To investigate the effectiveness and safety of the homeopathic product SilAtro-5-90 in recurrent tonsillitis.
Methods: In this international, pragmatic, controlled clinical trial, 256 patients (6-60 years) with moderate recurrent tonsillitis were randomized to receive either SilAtro-5-90 in addition to standard symptomatic treatment, or to receive standard treatment only. The primary outcome was the mean time period between consecutive acute throat infections (ATI) within 1 year (analyzed via repeated events analysis).