Publications by authors named "Vasyl S Naumchyk"
Article Synopsis
- The study presents a one-pot method for creating unsymmetrical 1,3,5-trisubstituted-1,2,4-triazoles through the coupling of amidines and carboxylic acids, followed by cyclization using hydrazines.
- The method achieved an 81% success rate in parallel synthesis and has the potential to generate over a billion unique chemical compounds.
- The created compound library includes over 10 million that meet lead-likeness criteria and 195 million sp-enriched compounds, making this method significant for advancements in medicinal chemistry.
