Comparison of the Effect of PRP, PRF and Induced Bleeding in the Revascularization of Teeth with Necrotic Pulp and Open Apex: A Triple Blind Randomized Clinical Trial.

Introduction: Treatment of a tooth with necrotic pulp and open apex is a special challenge to the clinicians. Apexification with calcium hydroxide and MTA barrier technique fails to induce continued root maturation which makes the tooth susceptible to root fracture. Hence, an ideal outcome for such a tooth should be regeneration of pulp like tissue into the root canal capable of continuing normal root maturation.

Reactive hyperplasic lesions of the oral cavity: A survey of 295 cases at a Tertiary Health Institution in Kerala.

Background: The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at a Tertiary Health Institution in Kerala and compare these data with those of previously reported studies.

Materials And Methods: The patient case files from the Department of Oral and Maxillofacial Pathology during the period between January 2007 and December 2011 were reviewed for cases of RHLs of the oral cavity. Both clinical and histopathological diagnoses of reactive lesions were selected for the study.

Management of a pathologically migrated upper anterior tooth using platelet-rich fibrin and a modified crown preparation technique.

In adult periodontal patients, pathologic tooth migration can create serious functional and aesthetic problems. In such situations, a combined orthodontic and periodontal treatment is often indicated. However, the lengthy treatment time and the demanding nature of orthodontic therapy for such periodontally compromised teeth is often a challenge.

Use of photoactivated disinfection and platelet-rich fibrin in regenerative Endodontics.

Aim: Photoactivated disinfection has been used as an adjunct to conventional endodontic treatment. Its use in regenerative endodontics is not reported in literature. The aim of this case report was to describe a new proposal for pulp revascularization with disinfection of pulp canal space using a unique combination of a photosensitizer solution and low-power laser light.

Invasive cervical root resorption: Engineering the lost tissue by regeneration.

Invasive cervical resorption (ICR) is a localized resorptive process that commences on the surface of the root below the epithelial attachment and the coronal aspect of the supporting alveolar process, namely the zone of the connective tissue attachment' early diagnosis, elimination of the resorption and restorative management are the keys to a successful outcome. Treatment done was a combined non-surgical root canal therapy, surgical treatment to expose the resorptive defect and the resorptive defect was filled up with reverse sandwich technique and finally the bony defect filled with platelet rich fibrin (PRF), hydroxylapatite and PRF membrane. Significant bone fill was obtained in our case after a 2 year follow-up period.

Novel management of avulsed tooth by pulpal and periodontal regeneration.

Introduction: The avulsion of anterior teeth of young children is a tragic occurrence and often presents an unparalleled challenge for the dentist. Reimplantation is the state-of-the-art treatment but may incur several complications, particularly with inappropriate posttraumatic management.

Methods: In this article we report the emergency and rehabilitation treatment of an avulsed maxillary anterior tooth by using platelet-rich fibrin.

Combination of platelet rich fibrin, hydroxyapatite and PRF membrane in the management of large inflammatory periapical lesion.

Periapical inflammatory lesion is the local response of bone around the apex of tooth that develops after the necrosis of the pulp tissue or extensive periodontal disease. The final outcome of the nature of wound healing after endodontic surgery can be repair or regeneration depending on the nature of the wound; the availability of progenitor cells; signaling molecules; and micro-environmental cues such as adhesion molecules, extracellular matrix, and associated non-collagenous protein molecules. The purpose of this case report is to add knowledge to the existing literature about the combined use of graft material [platelet rich fibrin (PRF) and hydroxyapatite (HA)] and barrier membrane in the treatment of large periapical lesion.

Platelet Rich Fibrin in the revitalization of tooth with necrotic pulp and open apex.

Regeneration of pulp-dentin complex in an infected necrotic tooth with an open apex is possible if the canal is effectively disinfected. The purpose of this case report is to add a regenerative endodontic case to the existing literature about using Platelet Rich Fibrin (PRF). A nine year old boy who accidently broke his immature maxillary central incisor tooth, developed pulpal necrosis with apical periodontitis.