Immunomodulatory therapy with anti-interleukin-1 after photorefractive keratectomy in the New Zealand white rabbit.

Purpose: To examine the safety and efficacy of topical anti-interleukin-1 (anti-IL-1) following photorefractive keratectomy (PRK) in rabbit eyes.

Setting: Joint Warfighter Refractive Surgery Center, Lackland Air Force Base, Texas, USA.

Design: Experimental study.

Visual outcomes after femtosecond laser in situ keratomileusis flap complications.

Purpose: To compare visual outcomes in normal and complicated laser in situ keratomileusis (LASIK) flaps constructed with a femtosecond laser.

Setting: Wilford Hall Ambulatory Surgical Center, San Antonio, Texas.

Design: Retrospective chart review.

Retrospective Analysis Comparing the Preoperative and Postoperative "Q" Values for 2 Different Lasers in Refractive Surgery.

Purpose: To compare the presurgical and postsurgical corneal asphericity, or "Q value," between VISX Wavefront-guided treatment and Allegretto Wave Wavefront-optimized treatment in photorefractive keratectomy for the correction of myopia.

Methods: This is a retrospective database analysis performed at the Joint Warfighter Refractive Surgery Center, Lackland Air Force Base, TX. All data were accessed through the Institutional Review Board-approved Joint Warfighter Refractive Surgery Center database.

The effect of silicone hydrogel bandage soft contact lens base curvature on comfort and outcomes after photorefractive keratectomy.

Objective: To evaluate the relative pain and the relative amount of contact lens loss experienced using two different base curvatures (BCs) of the Acuvue Oasys bandage soft contact lens (BSCL) after photorefractive keratectomy (PRK).

Methods: One hundred forty patients undergoing PRK on either the Allegretto or the VISX laser at the Joint Warfighter Refractive Surgery Center in Lackland AFB, TX, were randomized to one of the two different BCs of the Acuvue Oasys BSCL: 8.4 or 8.

Comparison of 3 silicone hydrogel bandage soft contact lenses for pain control after photorefractive keratectomy.

Purpose: To evaluate the relative pain with 3 U.S. Food and Drug Administration-approved bandage soft contact lenses (SCLs) applied after photorefractive keratectomy (PRK).

Pregabalin versus placebo in postoperative pain relief of patients' status post photorefractive keratectomy: a double-masked, randomized, prospective study.

Purpose: Gabapentinoids are currently being used anecdotally for postoperative pain following photorefractive keratectomy (PRK) despite the lack of evidence. The purpose of this study is to evaluate the effectiveness of pregabalin in mitigating pain after PRK compared to the standard of care.

Methods: One hundred thirty-five patients scheduled for PRK at the Joint Warfighter Refractive Surgery Center in San Antonio, Texas were randomized to receive either oral pregabalin 75 mg twice daily for 5 days or placebo, in addition to the standard pain care regimen.

Novel approach for the treatment of corneal ectasia in a graft.

Purpose: The aim of this study was to report the use of novel masking agents during an anterior lamellar keratoplasty performed using a femtosecond laser in a patient with corneal ectasia that was consistent with recurrent keratoconus.

Methods: This is a case report.

Results: A 55-year-old man, with a 23-year status after penetrating keratoplasty for keratoconus, presented with a chief complaint of ocular discomfort in the right eye.

Association of statin use with cataracts: a propensity score-matched analysis.

Importance: Cataracts are a main cause of low vision; with the growing elderly population, the incidence of cataracts is likely to increase. Investigators have previously hypothesized that statin antioxidant effects may slow the natural aging process of the lens.

Objective: To compare the risks for development of cataracts between statin users and nonusers.

Effect of topical immunomodulatory interleukin 1 receptor antagonist therapy on corneal healing in New Zealand white rabbits (Oryctolagus cunniculus) after photorefractive keratectomy.

Objectives: To compare topical interleukin 1 receptor antagonist (IL-1ra) to steroid treatment following photorefractive keratectomy (PRK) in rabbit eyes.

Methods: Our study is a randomized, investigator-masked study that was approved by the Institutional Animal Care and Use Committee. Following standard PRK, 48 eyes of 24 rabbits were divided into 5 arms: 4 treatment arms and 1 control arm.

Isolation of Kingella denitrificans from a corneal ulcer.

Purpose: To report a case of a corneal ulcer caused by an unusual pathogen.

Design: Case report.

Methods: Clinical review describing initial presentation, course, and outcome of 1 patient with a corneal ulcer caused by Kingella denitrificans.

Intrastromal corneal ring segments for post-LASIK ectasia complicated by persistent pain.

A 33-year-old man who was 2 years post laser in situ keratomileusis was found to have corneal ectasia. He was intolerant of rigid gas-permeable contact lenses and eventually chose to have placement of intrastromal corneal ring segments (ICRS) (Intacs) in the right eye. Two ICRS were implanted without complication, and postoperative examination showed improved visual acuity and decreased corneal elevation on scanning-slit tomography imaging.

Refractive surgery in the United States Air Force.

Purpose Of Review: Laser refractive surgery in the United States Air Force has developed into a robust program since its inception in 2001. The goal of this study is to summarize recent developments in the program. Presentations at national meetings, recently published articles, and unpublished data from ongoing studies in the area of photorefractive keratectomy and laser-assisted in-situ keratomileusis are discussed.

Review of sulfonamide-induced acute myopia and acute bilateral angle-closure glaucoma.

Sulfonamide medications can cause an idiosyncratic reaction, resulting in acute transient myopia and acute angle-closure glaucoma. The risk of an adverse reaction to a sulfonamide is approximately 3%, and the exact mechanism of the myopia and angle-closure glaucoma remains controversial. Typical clinical presentation includes bilateral involvement with blurring of vision that generally occurs over minutes to hours, nausea or vomiting, red eye, and headache.