Publications by authors named "Vasudev Bhat"
We report a neonate evaluated for hepatomegaly during hospitalisation and was diagnosed to have hepatoblastoma, an uncommon childhood malignancy. The presence of dysmorphism, macrosomia and congenital heart defect led to the suspicion of congenital overgrowth conditions. The genetic evaluation revealed a pathogenic variant, conclusive of Simpson-Golabi-Behmel syndrome type 1 (SGBS1).
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- This study aimed to evaluate the safety and effectiveness of adding carboplatin to craniospinal irradiation (CSI) for treating high-risk medulloblastoma patients, particularly those with significant residual tumors or leptomeningeal metastases.
- Conducted between 2005 and 2019 at a cancer center in India, 97 patients underwent carboplatin treatment alongside CSI, with most completing their planned therapy without major interruptions.
- Results indicated a 5-year progression-free survival rate of 60.2% and overall survival rate of 62.1%, with certain factors like type of metastasis impacting patient survival outcomes.