Publications by authors named "Vassiliki Ioannidou"
Article Synopsis
- The study compared traditional bacterial cultures with various PCR methods for diagnosing infections in patients undergoing total joint replacements, analyzing 44 samples for infection status.
- It found that standard cultures were more effective, with 20 samples testing positive for bacteria like S. epidermidis and S. aureus, while all isolates formed biofilms that showed high antimicrobial resistance.
- The findings suggest that the strong resistance linked to biofilm-forming bacteria could contribute to treatment failures, highlighting the need to consider biofilm presence in future treatment plans.
Background: Whipple's disease (WD) is a rare multisystemic bacterial infection, with variable clinical manifestations occasionally involving the central nervous system. As the cultivation of the etiologic agent, Tropheryma whippelii, is difficult, a laboratory diagnosis is usually based on histological methods. In the last few years, molecular detection of the bacterial 16SrRNA genes by PCR, with 2 primer sets, has greatly contributed to the ability of clinicians to diagnose this disease.
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