Demyelination in Patients with POST-COVID Depression.

Depression is one of the most severe sequelae of COVID-19, with major depressive disorder often characterized by disruption in white matter (WM) connectivity stemming from changes in brain myelination. This study aimed to quantitatively assess brain myelination in clinically diagnosed post-COVID depression (PCD) using the recently proposed MRI method, macromolecular proton fraction (MPF) mapping. The study involved 63 recovered COVID-19 patients (52 mild, 11 moderate, and 2 severe) at 13.

[Species-specific localization of DNA from pericentromeric heterochromatin on polytene chromosomes in the salivary gland cells and 3D-nuclear organization nurse cells in Drosophila virilis, and Drosophila kanekoi (Diptera: Drosophilidae)].

Microdissection of the chromocenter of D. virilis salivary gland polytene chromosomes has been carried out and the region-specific. DNA library (DvirIII) has been obtained.

[Molecular-cytogenetic analysis of pericentromeric heterochromatin in ovarian nurse cells of Drosophila melanogaster subgroup species].

Evolutionary rearrangements of pericentromeric heterochromatin among Drosophila melanogaster subgroup species have been investigated. Region-specific DNA library from Drosophila orena ovarian nurse cell chromocenter has been obtained by microdissection of polytene chromosomes. The probe was localized on ovarian nurse cells chromosomes of D.

[The effects of inbreeding and low temperature on the pattern of chromosome synapsis in the ovarian nurse nuclei of Drosophila melanogaster strains].

The effects of inbreeding and low temperature on the pattern of homologous chromosome synapsis in ovarian nurse cell nuclei of Drosophila melanogaster strains were studied. Exposure to decreased temperature (16 degrees C) caused a noticeable increase in the rate of asynapses of homologous chromosomes, whereas this effect was insignificant for F30 inbreeding generation. Long-term inbreeding has a substantial effect on the relative positions of chromosomes in the nurse cell nuclei.

[Visualization of chromosome territories in interphase nuclei of ovarian nurse cells in Calliphora erythrocephala Mg. (Diptera: Calliphoridae)].

Analysis of localization of chromosomes 2, 3, and 6 of Calliphora erythrocephala Mg. in ovarian nurse cell nuclei with different chromatin structure has shown that the regions of DNA probe hybridization reduced with increasing chromatin compaction. Hybridization of DNA probes of chromosomes 3 and 6 to secondary reticular nuclei demonstrated that chromosomes retain their territories in the nuclei when the chromatin acquires a reticular structure.

[Organization and differential staining of chromosomes from the endomitotic nucleus of trophocytes Calliphora erythrocephala (Diptera: Calliphoridae)].

The structure of primary polytene chromosomes and general architecture of nurse cell nuclei was studied in Calliphora erythrocephala using various methods of differential chromosome banding(G-, R-, C-banding; Ag- and DAPI staining), chromospecific DNA probes and fluorescence in situ hybridization. This analysis revealed differential compaction of particular chromosome regions. The localization of material of polytene chromosome 6 is retained after its rearrangement and the formation of the internal reticular structure of the nucleus.

[Alteration of chromosome structure in ovarian nurse cells of Drosophila melanogaster by hybrid dysgenesis].

The impact of hybrid dysgenesis on the chromosome structure of Drosophila melanogaster ovarian nurse cells was studied. In the examined lines and interlinear hybrids (including those yielded by dysgenic crosses in the P-M and I-R systems of hybrid dysgenesis), disturbed chromosome synapsis was revealed. The disturbance was somewhat similar to that observed in interspecific hybrids.

[Attachment of polytene chromosomes to the nuclear envelope in ovarian pseudonurse cells in Drosophila melanogaster].

Certain aspects of the polytene chromosome attachment to the nuclear envelope (NE) of ovarian pseudonurse cells (PNC) in the mutant strains otu11 and fs(2) B of Drosophila melanogaster were studied. In contrast to salivary a local chromocenter and Rable-orientation of chromosomes were shown to be missing from the PNC nuclei. The pericentric regions were scattered in the nuclear space and were obliged to attach to the NE by specific loci of heterochromatin.

[Organization of the primary polytene chromosome in the ovaries of 12 species of the "virilis" group of the genus Drosophila (Sophophora)].

Organization of chromosomes was analyzed in ovarian nurse cells in 12 species of the virilis group of Drosophila. A diffuse chromocenter containing a clearly detectable block of heterochromatin was shown to be characteristic of the phylogenetically ancestral species D. virilis and D.

[Spatial organization of chromosomes in oocytes and spermatocytes in malaria mosquitos].

It is shown that prophase chromosomes of oocytes in Anopheles messeae ovaries do not form local chromocenters, unlike spermatocytes, in which chromosomes fuse in a joint centromeric assembly. This fact reflects the dynamic nature of the system of chromocenter formation in generative tissues. During analysis of interspecific hybrids F1 A.

[Species architecture of generative tissue chromosomes and problems of phylogenetic relationships in the melanogaster subgroup of the Drosophila genus (Sophophora)].

An analysis was carried out of the peculiarities of interlocation of primary ovarian trophocyte polytene chromosomes of Drosophila sechellia in comparison with seven earlier-described species of the melanogaster subgroup. Based on the data from this analysis and earlier-known results of reconstruction of the reconstruction of the subgroup phylogeny, the following trend in the evolution of the architectonics of trophocyte chromosomes is suggested: from a local tight chromocenter (D. orena), to a diffuse chromocenter (D.

[Interspecies differences of co-orientation of primary polytene chromosomes in ovarian nurse cells in Drosophila melanogaster, D. simulans and D. mauritiana].

Essential differences in the architecture of primary polytene chromosomes in ovarian nurse cells between Drosophila melanogaster, D. simulans and D. mauritiana were discovered.

[The interrelation of the polytene chromosomes of generative tissues in Drosophila melanogaster].

The principles of three dimensional organization of primary and secondary orders polytene chromosomes in ovarian nurse cells of Drosophila melanogaster were elucidated. Contrary to somatic tissues, no joining of chromosome arms into local chromocentre was discovered. The chromosomes are separated in the nuclear space and are attached to the nuclear envelope by the centromeric (and the XL arm--by the telomeric) sites, the arms of autosomes (especially primary polytene chromosomes) being separated in the area of attachment.