Quality of electronic records documenting adverse drug reactions within a hospital setting: identification of discrepancies and information completeness.

Aim: Incomplete and incorrect documentation of adverse drug reactions (ADRs) can restrict prescribing choices resulting in suboptimal pharmaceutical care. This study aimed to examine the quality of information held within electronic systems in a hospital setting, to determine the preciseness of ADR documentation, and identify discrepancies where multiple electronic systems are utilised.

Method: Over a four-week period, consecutive patients admitted to the general medical ward at the study hospital had their electronic profiles reviewed.

Chromosomal evolution in gazelles.

The chromosomes of nine gazelle species and two other Antilopinae species (Antidorcas marsupialis and Antilope cervicapra) were prepared from fibroblast cultures. G- and C-band karyotypes were constructed, and when possible, autosomal arms were numbered according to the cattle standard karyotype. Diploid chromosome numbers ranged from 30 to 58.

Genetic study of Gazella gazella: chromosomal and allozymic data.

Some subspecies of Gazella gazella are studied by means of protein electrophoresis (gazella, cora, and erlangeri) and cytogenetics (gazella, cora, erlangeri and farasani), and are compared to G. subgutturosa. Variability parameters and genetic distances are computed from allozyme data at 24 loci.

Serum chemistry values for Arabian sand gazelles (Gazella subgutturosa marica).

Values for urea, creatinine, glucose, total bilirubin, sodium, potassium, chloride, calcium, phosphates, magnesium, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, lactate deshydrogenase, and creatine-kinase are reported for the first time for 32 sand gazelles (Gazella subgutturosa marica) in Saudi Arabia. Comparisons were made between two groups: one sampled before a trip and the other sampled after a 14 hr trip. Only aspartate aminotransferase was higher in the second group; magnesium and phosphates were lower in that group.

Chromosomal polymorphism in sand gazelles (Gazella subgutturosa marica).

A total of 84 Gazella subgutturosa from three captive populations (two in Saudi Arabia, one in Qatar) were karyotyped. The number of chromosomes is 33, 32, or 31 for the males and 32, 31, or 30 for the females because of the X-autosome translocation that is common in the genus and a centric fusion between the two pairs of acrocentric chromosomes. The G- and R-banded karyotypes of gazelles translocated show that this fusion is the same as that previously reported for gazelles from Jordan.

Chlamydiosis in a captive group of Houbara bustards (Chlamydotis undulata).

A chlamydiosis outbreak occurred in a Houbara bustard (Chlamydotis undulata) captive breeding group in Saudi Arabia, inducing peracute deaths, highly variable clinical signs, and pathological and histological lesions. Typical inclusion bodies in stained impression smears of spleen and prevalence (80%) of antibodies against Chlamydia, detected by a competitive enzyme immunoassay test, provided the bases for the diagnosis. This is the first report on a chlamydiosis outbreak in birds of the family Otididae.

Pharmacokinetics of doxycycline after parenteral administration in the Houbara bustard (Chlamydotis undulata).

Fourteen adult Houbara bustards (Chlamydotis undulata) infected with Chlamydia psittaci were administered doxycycline at 100 mg/kg body weight in seven intramuscular or subcutaneous injections at intervals of 7, 7, 7, 6, 6, and 5 days. Blood levels of doxycycline were measured after the first and seventh injections at the following intervals: 0, 12, 24, 36, 48, 72, 96, 120, 144, 168, and 180 hours. During these two periods, most of the birds showed plasma doxycycline levels in excess of 1 micrograms/ml, demonstrating effective doxycycline levels for 45 days.

An unusual Gazella dama karyotype.

The chromosomes of a female gazelle (Gazella dama) were investigated using GTG, RBG and C banding techniques. Their banding patterns showed that autosomes are involved in a complex of four Robertsonian translocations.

Biochemical parameters following capture myopathy in one Arabian oryx (Oryx leucoryx).

Twenty-three biochemistry parameters and hematocrit were followed during 10 days in a 13 months old Arabian Oryx (Oryx leucoryx) during capture myopathy. An increase was found in bilirubin, creatine-kinase, alanine aminotransferase, and aspartate aminotransferase levels, but not in potassium level. Most of the parameters analyzed were the first given for this species.

Serological survey for bovine bacterial and viral pathogens in captive Arabian oryx (Oryx leucoryx Pallas, 1776).

Tests for antibodies to bovine bacterial and viral pathogens were conducted on 239 sera from 128 Arabian oryx (Oryx leucoryx) from seven locations (Taif, Riyadh and Mahazat as Said, Saudi Arabia; San Diego, United States of America [USA]; Shaumari, Jordan; Qatar; and Bahrain). No antibodies to Pasteurella multocida type E or epizootic haemorrhagic disease 1 virus were found. Antibodies to Brucella abortus, P.

Capripoxvirus disease in an Arabian oryx (Oryx leucoryx) from Saudi Arabia.

Lumpy skin disease caused by a capripoxvirus was observed in a captive-bred female Arabian oryx (Oryx leucoryx) at the National Wildlife Research Center, Taif, Saudi Arabia. Clinical signs included severe general depression with fever, anorexia, greater than 1,000 nodular cutaneous lesions and gradual recovery over 2 mo. The virus was found by electron microscopy and paired sera showed an increasing virus neutralization antibody titer against capripoxvirus.

Hematological and serum chemistry values for Arabian oryx (Oryx leucoryx).

Blood samples obtained from 73 captive Arabian oryx (Oryx leucoryx) were analyzed for hematology and serum chemistry values. Compared with other data from this animal RBC, WBC, bilirubin and ASAT values are lower, but glucose, urea and uric acid values are higher.