Nuclear scintigraphy findings for Askin tumor with In111-pentetreotide, Tc99m-MIBI and F18-FDG.

Askin tumor is a rare disease which had previously been reported as being thallium-201 and gallium-67 avid. Varying data regarding 18F- fluorodeoxyglucose metabolism has been described with Ewing family of soft tissue tumors. In this case, we present a patient found to have an Askin tumor of the left chest wall which demonstrated indium-111 pentetreotide and technetium-99m MIBI avidity.

Hyperinsulinism presenting in childhood and treatment by conservative pancreatectomy.

Objective: To describe the uncommon presentation of hyperinsulinism in an 8-year-old boy.

Methods: We describe the patient's clinical findings, results from biochemical and imaging studies, surgical approach, and outcome. The discussion encompasses a review of literature that provided the basis for the diagnostic and surgical approach applied to this patient's case.

Relative hyperperfusion by SPECT in a family with a presenilin 1 (T245P) mutation.

Clinical characteristics of autosomal dominant Alzheimer's disease often differ clinically from sporadic disease with the onset of seizures, spasticity and myoclonus early in the disease course. Similarly imaging characteristics may also differ. We report the findings of relative hyperperfusion by Tc-99m HMPAO SPECT in the medial orbitofrontal cortex and anterior temporal lobe in four affected family members carrying a presenilin 1 mutation.

Rapid detection of acute appendicitis with Tc-99m-labeled intact polyvalent human immune globulin.

Background: Acute appendicitis remains problematic for emergency clinicians. A rapid and definitive test is needed for detecting acute appendicitis before surgical intervention. The purpose of this clinical trial was to determine the efficacy of Tc-99m-labeled intact polyvalent human immune globulin (Tc-99m IgG) in the evaluation of acute appendicitis.

Importance of the lateral view in the evaluation of suspected brain death.

The authors present two cases of clinical brain death that failed to meet the criteria for whole brain death using Tc-99m HMPAO. Conventional anterior cerebral flow studies demonstrated no intracerebral perfusion. Anterior static images also failed to show cerebral activity.

Scintigraphic detection of atherosclerotic plaques in rabbits with 111In-labeled hematoporphyrin derivative.

The efficacy of 111In-labeled hematoporphyrin derivative (HPD) in localizing and detecting atheromas had been investigated with 10 atherogenic New Zealand white rabbits. Atherosclerotic plaques surgically induced in the abdominal aorta showed selective uptake of 111In-HPD over normal blood vessels averaging 0.01% ID/g tissue (range 0.

Bone imaging findings in gangrene.

Review of three-phase bone imaging results in three patients with gangrene of the toes showed a unique pattern of absent perfusion and absent bony and soft-tissue uptake. In one of these patients, characteristic bone imaging findings were present before clear-cut clinical presentation. In our experience, the finding of absent uptake in a particular clinical setting is highly specific for gangrene.

Albumin lung/heart ratio change. A simple clinical means of documenting increased pulmonary endothelial permeability to protein.

We investigated a simple method that can be used at the bedside for documenting the net accumulation of albumin in the lung. The technique employs measurement with a computer-linked gamma camera of the activity ratio in an area of the right lung compared with the same-sized area in the heart at 20 minutes and three hours following intravenous injection of technetium Tc 99m albumin. We applied this measurement to three groups of patients: a control group and patients with roentgenographic evidence of edema classified according to clinically available criteria as either hydrostatic edema or permeability edema to see if we could document differences among these groups.

Carney's triad: radiographic diagnosis, natural history and importance of pulmonary chondromas.

We describe the radiographic findings and benign clinical course of a patient with two components of a triad of unusual neoplasms: pulmonary chondroma, gastric epithelioid leiomyosarcoma, and paraganglioma that may occur together in young women.

The relationship between radiographic findings and asymmetrical radioactivity in the shoulder.

A prospective study was performed to compare asymmetrical radioactivity in the shoulder on 99mTc bone scans with the conventional radiographic findings of 100 right-handed and 8 left-handed patients. Of the 100 right-handed patients, 30 had increased radioactivity in the right shoulder; 5 showed increased radioactivity on the left. Clinical history, shoulder physical examination, and site of injection did not influence the frequency of asymmetrical radioactivity; only dominant handedness correlated with this finding.