Publications by authors named "Vasily A Isakov"

Article Synopsis
  • Constipation-predominant irritable bowel syndrome (IBS-C) primarily affects women, and traditional dietary changes often fail due to poor adherence; functional foods like kombucha may improve compliance and symptoms.
  • A pilot study tested the effectiveness of kombucha enriched with inulin and vitamins in 40 women with IBS-C, comparing it to a control group receiving water over 10 days.
  • Results showed that the kombucha group had significantly increased stool frequency, improved stool consistency, and reduced feelings of incomplete bowel emptying compared to the control group, indicating potential benefits for managing IBS-C symptoms.
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Chronic hepatitis B (CHB) infection is one of the most common causes of cirrhosis and liver cancer worldwide. Our aim was to assess clinical and patient-reported outcome (PRO) profile of CHB patients from different regions of the world using the Global Liver Registry. The CHB patients seen in real-world practices are being enrolled in the Global Liver Registry.

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Background & Aims: Globally, nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease. We assessed the clinical presentation and patient-reported outcomes (PROs) among NAFLD patients from different countries.

Methods: Clinical, laboratory, and PRO data (Chronic Liver Disease Questionnaire-nonalcoholic steatohepatitis [NASH], Functional Assessment of Chronic Illness Therapy-Fatigue, and the Work Productivity and Activity Index) were collected from NAFLD patients seen in real-world practices and enrolled in the Global NAFLD/NASH Registry encompassing 18 countries in 6 global burden of disease super-regions.

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Article Synopsis
  • * It included 120 participants aged 40-70 over a period of 56 days, split into two groups receiving either the VMP or a placebo, with various blood nutrient levels and heart health biomarkers measured throughout.
  • * Results showed that VMP supplementation increased key nutrients like quercetin and vitamin C, while also reducing harmful heart health markers such as homocysteine and gamma-glutamyl transferase, suggesting overall heart health benefits from the VMP.
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