Publications by authors named "Vasilli Kasimov"

Article Synopsis
  • * This study analyzed 263 samples from healthy livestock and abortion cases in Switzerland to understand strain diversity using genetic testing techniques, revealing novel genotypes and significant genetic diversity in bovine strains compared to lower diversity in sheep and pig strains.
  • * It found that all sheep and pig samples contained a specific plasmid, while only about 69.4% of bovine samples did; no plasmid was detected in the abortion cases, suggesting possible unique strain characteristics or detection issues.
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an obligate intracellular bacterium, is a major causative agent of reproductive loss in ruminants, with zoonotic potential. Though this pathogen is primarily known to infect livestock, recent studies have detected and isolated genetically distinct avian strains of from wild birds globally. Before this study, only five avian genomes were publicly available.

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Article Synopsis
  • The study examines a globally distributed veterinary pathogen with zoonotic potential, highlighting challenges in isolating and culturing it which hinder the understanding of its genetic diversity, especially in avian hosts from Australia and New Zealand.
  • Researchers utilized culture-independent whole-genome sequencing to discover new genomes from various birds, including pigeons and parrots, revealing unique genetic sequences and characters.
  • The findings showcase significant genetic diversity, with specific strains identified in different bird species and environments, enhancing knowledge of the pathogen’s global diversity and its capability to thrive in multiple host species.
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  • The genus discussed contains significant bacterial pathogens that affect both humans and animals, influencing the study of disease.
  • Since the publication of the first chlamydial genome in 1998, significant advancements in our understanding of these bacteria's interactions and adaptations within host environments have occurred.
  • The review focuses on developments in genomics, including whole genome sequencing and multi-omics approaches, which have greatly enhanced our insights into virulence, evolution, and future research directions in chlamydial pathogenesis.
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Birds may act as hosts for numerous pathogens, including members of the family , (BFDV), avipoxviruses, (CoAHV1) and (PsAHV1), all of which are a significant biosecurity concern in Australia. While and BFDV have previously been detected in Australian avian taxa, the prevalence and host range of avipoxviruses, CoAHV1 and PsAHV1 in Australian birds remain undetermined. To better understand the occurrence of these pathogens, we screened 486 wild birds (kingfisher, parrot, pigeon and raptor species) presented to two wildlife hospitals between May 2019 and December 2021.

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  • The avian pathogen poses a risk to both animals and humans, particularly causing reproductive loss in horses and subsequent infections in humans who come into contact with them.
  • A study analyzed genomic data from various species, revealing that predominant strains (ST24) showed clonal characteristics across horses, birds, and humans, primarily in Australia, while also identifying significant genomic diversity in other groups.
  • Findings indicated that ST24 has distinct sub-lineages with recent population expansion, highlighting the potential for cross-species transmission within its various hosts.
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  • Birds can carry germs that can make both animals and humans sick, including a type called Chlamydia.
  • In a study, scientists checked 564 birds in Australia and found that nearly 30% had Chlamydia, with some able to make people sick.
  • They discovered new types of Chlamydia in more bird species than expected, which means there might be a greater risk of spreading these germs to other animals and humans.
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Traditional methods of detecting in tissue samples such as polymerase chain reaction or cell culture are laborious and costly. We evaluated the use of a previously developed LAMP assay using minimally processed ovine samples. Cotyledon ( = 16), foetal liver ( = 22), foetal lung ( = 2), and vaginal ( = 6) swabs, in addition to cotyledon ( = 6) and foetal liver ( = 8) tissue samples, were rapidly processed and used for LAMP testing without DNA extraction.

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is traditionally regarded as a globally distributed avian pathogen that can cause zoonotic spill-over. Molecular research has identified an extended global host range and significant genetic diversity. However, Australia has reported a reduced host range (avian, horse, and human) with a dominance of clonal strains, denoted ST24.

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  • Researchers tested oropharyngeal swabs from 80 wild-caught and spleen samples from 87 euthanased koalas in South Australia to check for Phascolarctid gammaherpesviruses (PhaHV) using PCR assays.
  • They found that 72.5% of wild-caught koalas actively shed PhaHV, including both subtypes, with 72.4% of euthanased koalas showing systemic infection and 54% actively shedding the virus.
  • Additionally, shedding patterns revealed that koalas shedding PhaHV-2 were more likely to shed both viral subtypes, and relationships were noted between BCS (Body Condition Score) and shedding in euthanased ko
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