Novel Digital Biomarkers for Fine Motor Skills Assessment in Psoriatic Arthritis: The DaktylAct Touch-based Serious Game Approach.

Psoriatic Arthritis (PsA) is a chronic, inflammatory disease affecting joints, substantially impacting patients' quality of life, with European guidelines for managing PsA emphasizing the importance of assessing hand function. Here, we present a set of novel digital biomarkers (dBMs) derived from a touchscreen-based serious game approach, DaktylAct, intended as a proxy, gamified, objective assessment of hand impairment, with emphasis on fine motor skills, caused by PsA. This is achieved by its design, where the user controls a cannon to aim at and hit targets using two finger pinch-in/out and wrist rotation gestures.