α7 nicotinic acetylcholine receptors induce long-term synaptic enhancement in the dorsal but not ventral hippocampus.

Agents that positively modulate the activity of α7nAChRs are used as cognitive enhancers and for the treatment of hippocampus-dependent functional decline. However, it is not known whether the expression and the effects of α7nAChRs apply to the entire longitudinal axis of the hippocampus equally. Given that cholinergic system-involving hippocampal functions are not equally distributed along the hippocampus, we comparatively examined the expression and the effects of α7nAChRs on excitatory synaptic transmission between the dorsal and the ventral hippocampal slices from adult rats.

Accuracy of Direct Composite Veneers via Injectable Resin Composite and Silicone Matrices in Comparison to Diagnostic Wax-Up.

Purpose: To evaluate the discrepancy between the diagnostic wax-up and the resulting direct veneers using different matrices. Materials and method: A total of 48 identical misaligned models, 12 wax-up models and one ‘every other tooth’ wax-up model were 3D printed. Group 1: Transparent silicone matrices with holes for the injection of the flowable composite.