Assessing the clinical utility of Wnt pathway markers in colorectal cancer.

Purpose: β-catenin and AXIN2 play an important role in the Wnt signaling pathway. The aim of this study was to investigate β-catenin and AXIN2 expression in colorectal cancer (CRC) and relate these findings with patients' clinicopathological features and prognosis.

Methods: 57 consecutive patients with surgically treated CRC were included in this study.