Publications by authors named "Vasileios K Kimiskidis"

Article Synopsis
  • Epileptic patients often experience cognitive impairments, particularly in memory, attention, and executive functions, which can vary based on the location of epileptic activity; this study focuses on MRI-negative epilepsy patients.
  • By enrolling 20 MRI-negative epilepsy patients and 10 age-matched controls, the research utilized auditory event-related potentials (ERPs) and the EpiTrack cognitive tool to assess cognitive functions.
  • Results showed prolonged P300 latencies and poor performance on cognitive tests in epilepsy patients compared to controls, indicating significant cognitive decline related to memory, attention, and information processing speed.
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Background And Aims: Epilepsy is the most common serious neurological disorder worldwide. Approximately 40% of patients with focal epileptic seizures remain uncontrolled with antiepileptic drug (AED) monotherapy or polytherapy. Lacosamide has been recently approved by the European Medicines Agency as monotherapy for the treatment of focal seizures.

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We present a case of a 74-year-old Greek male who suffered from paraphasias, memory and orientation problems. The patient was assessed with neuropsychometric tests, auditory event-related potentials and cerebrospinal fluid proteins and was diagnosed with mild cognitive impairment. The emphasis on the case is on the unexplained high levels of P300 and Slow wave of the auditory event-related potentials.

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