Artificial intelligence to improve ischemia prediction in Rubidium Positron Emission Tomography-a validation study.

Background: Patients are referred to functional coronary artery disease (CAD) testing based on their pre-test probability (PTP) to search for myocardial ischemia. The recommended prediction tools incorporate three variables (symptoms, age, sex) and are easy to use, but have a limited diagnostic accuracy. Hence, a substantial proportion of non-invasive functional tests reveal no myocardial ischemia, leading to unnecessary radiation exposure and costs.

Use of artificial intelligence to assess the risk of coronary artery disease without additional (non-invasive) testing: validation in a low-risk to intermediate-risk outpatient clinic cohort.

Objectives: Predicting the presence or absence of coronary artery disease (CAD) is clinically important. Pretest probability (PTP) and CAD consortium clinical (CAD2) model and risk scores used in the guidelines are not sufficiently accurate as the only guidance for applying invasive testing or discharging a patient. Artificial intelligence without the need of additional non-invasive testing is not yet used in this context, as previous results of the model are promising, but available in high-risk population only.

EFFICACY OF RADIOSURGERY IN TREATMENT OF MALIGNANT TUMOR OF LARYNX.

The aim of the work was to evaluate the effectiveness of the radiosurgery method in the treatment of malignant tumors of the larynx. The treatment of 48 patients was carried out using the "Rocus-AM" device. The larynx was irradiated 5 times a week, with a single focal dose of 2.

Small Polarons in Two-Dimensional Pnictogens: A First-Principles Study.

We report the first-principles study of small polarons in the most stable two-dimensional pnictogen allotropes: blue and black phosphorene and arsenene. While both cations and anions of small hydrogen-passivated clusters show charge localization and local lattice distortions, only the hole polaron in the blue allotrope is stable in the infinite size cluster limit. The adiabatic polaron relaxation energy is found to be 0.

[Structural and functional features of peripheral vasculature in patients with glaucoma].

Purpose: To study the reactivity of the vascular endothelium and the elastic properties of the upper and lower extremities, and assess the vascular innervation effect of Cytoflavin in patients with stable and rapidly progressive primary open-angle glaucoma (POAG).

Material And Methods: The study included 67 patients with POAG (mean age 66.3±1.

[Bilateral occlusion of retinal vessels in Waldenstrom's disease (a case study)].

The article describes a clinical case of bilateral occlusion of retinal vessels in a patient with Waldenstrom's disease - a rare lymphoplasmocytic tumor of the bone marrow characterized by a complex of syndromes, among which the syndrome of blood hyperviscosity dominates. Comprehensive clinical, instrumental and laboratory examinations revealed that besides the syndrome of blood hyperviscosity the patient also had loci of cerebral ischemia (according to magnetic resonance imaging), ocular hypoperfusion with severe deficiency of retinal and choroidal blood flow (according to Doppler methods) indicating the presence of ocular ischemic syndrome. Since bilateral occlusion of retinal vessels without concomitant vascular and/or systemic pathology is rare, patients with such diagnosis should be referred to a hematologist.

A new non-invasive diagnostic tool in coronary artery disease: artificial intelligence as an essential element of predictive, preventive, and personalized medicine.

Background: Known coronary artery disease (CAD) risk scores (e.g., Framingham) estimate the CAD-related event risk rather than presence/absence of CAD.

[Clinical picture, diagnostics and prophylaxis of a syndrome in conditions of the Far North].

The analysis of a clinical picture barometeosensitivity in a seaside zone of the Far North is carried out in the article. A diagnostic test included the following laboratory assessments: complete blood count, complete urinary analysis, biomedical measurement assessment, immunology blood research and functional renal test; analysis of the level of an electrolyte in the blood and hormone receptor status; and the following instrumental diagnostics: The auscultatory Korotkov's method of determining blood pressure, electrocardiography, variational pulsometry, chest X-ray, mechanocardiography, echocardiography and abdominal ultrasound; and also consultation of ophthalmologist and neuropathologist. Every patient should keep a diary "weather - health" before and after the treatment.

Surgical management of patients with pathological deformities of carotid arteries.

Surgical management of pathological deformities of the internal carotid arteries, a cause of chronic brain ischemia, is discussed. This pathology is very common and is found in 25% of all individuals who underwent preventive medical examination according to the ultrasonography data. Most deformities do not pose any threat to patients, while some of them may cause ischemic stroke and chronic brain ischemia.

[The natural resources of the expedition bay as a basis for the creation of the health resort centre at the coast of the Peter the Great Bay, the Sea of Japan].

The present article presents characteristics of the therapeutic and health promoting potential of the Expedition Bay, (part of the Peter the Great Bay, the Sea of Japan), known to be a deposit of therapeutic sea muds. The great variety of local therapeutic natural resources, viz. sea muds, sea weeds, friendly climate, beeches, etc.

Photoionization of radiation-induced traps in quartz and alkali feldspars.

For the optimization of luminescence dating and dosimetry techniques on the basis of the optically stimulated luminescence, the stimulation spectra of quartz and alkali feldspars were measured in the spectral region of 250-1100 nm using optically stimulated afterglow. Optically stimulated luminescence in all studied spectral regions is induced by the same kind of deep traps, that produce thermoluminescence in the regions of palaeodosimetric peaks for both minerals. The mechanism for photoionization of deep traps was proposed as being due to delocalization of the excited state of the corresponding lattice defects.

[The treatment of patients with acute colonic ileus of tumoral genesis at the general surgery department].

The results of treatment of 57 patients with an acute ileus (AI), caused by colonic cancer, were analyzed. The compensated (in 9 patients), sub-compensated (in 35) and decompensated (in 13) forms of AI were assigned. In the right-sided localization of tumor or left-sided one and compensated AI the one-stage radical operation was done.

[The protective properties of the lysosomal form of Pseudomonas aeruginosa anatoxin in a test of its active protection of experimental animals].

The protective activity of the liposomal form of P. aeruginosa toxoid and intact phosphatidylethanolamine liposomes has been evaluated in mice with experimental P. aeruginosa infection.

[Surgical treatment of recurrent inguinal hernia].

The experience with surgical treatment of 89 patients with recurrent inguinal hernia is presented. A method for hernioplasty with the use of the pyramidal muscle transferred for covering the inguinal space is described. In 37 patients, no hernia recurrence and injury to the femoral vessels were revealed.

[The surgical treatment of large ventral hernias in middle-aged and elderly patients].

Changes of intra-abdominal pressure, the degree of abdominal wall stretching, the strength of connection of the tissues and the quality of the operative wound, central hemodynamics, and the indices of external breathing were studied depending on the type of hernioplasty in 44 animals (dogs) and 420 patients with large ventral hernias. The authors suggest a method for surgical treatment of ventral hernias by twisted aponeurotic sutures applied under control of intraabdominal pressure. With the use of this method the number of complications in the main group reduced 3.

[Experimental and clinical study of nitazol as an antibacterial drug in the complex treatment of peritonitis].

Antibacterial properties of the Soviet drug nitazol which is a derivative of imidazole were studied. It was shown that nitazol in a dose of 4-8 micrograms/ml was highly active against gram-negative nonsporulating anaerobes, gram-positive anaerobic cocci and spore-forming Clostridia spp. Unlike metronidazole, it was efficient against both standard and clinical strains of facultative anaerobes such as E.

[Evaluation of liposomal forms of rifampicin and prodigiozan in the treatment of experimental chronic tonsillitis].

Therapeutic effect of liposomal dosages of rifampicin and prodigiozan was studied on rabbits with simulated chronic tonsillitis in comparison to that of commercial ones of the drugs. The treatment schemes included daily intra-tonsillar++ injections of the dosage forms for 5 days. A high efficacy of their liposomal dosage forms in treatment of experimental chronic tonsillitis was confirmed microbiologically and immunologically.

[Antibacterial activity of nitazole and its use in combined treatment of appendicular peritonitis in children].

The experimental-clinical investigations have demonstrated the high effectiveness of the native preparation Nitazole against the Gram-negative non-spore-forming anaerobic bacteria, Gram-positive anaerobic cocci, spore-forming Clostridium, certain facultative anaerobes. This permits to recommend it for the use as an antibacterial preparation for the treatment of peritonitis in children.

[Diagnostic and therapeutic choices in lung diseases complicated by hemorrhage].

The results of treatment of 76 patients with various diseases of the lungs complicated by hemorrhage are analysed. A complex of diagnostic and therapeutic measures were applied in a certain order, including bronchoscopy with temporary occlusion of the bronchi, bronchial arteriography with acute embolization of the bronchial artery. Hemorrhage was arrested in 73 patients with the use of such tactics, in 48 of them an economical operative intervention was carried out.

[Immunogenic properties of the liposomal form of Pseudomonas aeruginosa anatoxin].

Studies of immunogenic properties of P. aeruginosa anatoxin incorporated into liposomes of varying lipid compositions have shown that single immunization of mice with the anatoxin included into phosphatidyl ethanolamine and lecithin cholesterol liposomes induces a 6-8-fold higher antitoxin antibodies production than immunization with unadsorbed or adsorbed on aluminum hydroxide P. aeruginosa toxoid.

[Oxygen and hemodynamic support for physical load in neurocirculatory dystonia].

Spiroergometric examinations were carried out in 148 students with neurocirculatory dystonia. The adaptation reaction of the cardiorespiratory system to different load strength was studied. The authors used a complex approach with evaluation of the functional parameters of the heart, indices of central hemodynamics and analysis of respiratory gases.