Dissipative dynamics of multiple-quantum NMR coherences in two-spin systems.

Multiple-quantum (MQ) NMR experiments were performed at a special orientation of a hambergite (BeBOOH) single crystal, which consists of alternating zigzag proton chains. At the chosen orientation, one of the dipolar coupling constants in the chain becomes zero and the system becomes a set of well-isolated dipolar coupled spin pairs. The relaxation of the spin pairs in the MQ NMR experiment was studied on the basis of the Lindblad equation.

Anthraquinone-Quinizarin Copolymer as a Promising Electrode Material for High-Performance Lithium and Potassium Batteries.

The growing demand for cheap, safe, recyclable, and environmentally friendly batteries highlights the importance of the development of organic electrode materials. Here, we present a novel redox-active polymer comprising a polyaniline-type conjugated backbone and quinizarin and anthraquinone units. The synthesized polymer was explored as a cathode material for batteries, and it delivered promising performance characteristics in both lithium and potassium cells.

H multiple quantum NMR in alternating quasi-one-dimensional spin chains of hambergite.

Multiple quantum (MQ) dynamics was investigated in quasi-one-dimensional H zigzag spin chains in hambergite (BeBOOH) single crystals. Due to the non-linear arrangement of the spins, dipolar coupling strengths alternate along the chain. To solve the problem of MQ NMR experiments taking too much time due to extremely long H spin-lattice relaxation times, the samples were exposed to gamma irradiation to produce the defects accelerating the relaxation.

Cellulose from Annual Plants and Its Use for the Production of the Films Hydrophobized with Tetrafluoroethylene Telomers.

Cellulose was produced by the modified traditional method with 35% yield from the stem of Sosnovsky hogweed and was characterized by elemental analysis, infrared (IR) spectroscopy, powder X-ray diffractometry, differential scanning calorimetry (DSC) and X-ray photoelectron spectroscopy (XPS). For , the degree of crystallinity (approximately 70%) and the glass transition temperature (105-108 °C) were determined. It was found that the whiteness characteristic in the case of was 92% and this significate was obtained without a bleaching procedure using chlorine-containing reagents.

[Clinical results and prospects for the use of phenosanic acid in patients with focal epilepsy].

Objective: To study the efficacy and safety of using a new original synthetic antioxidant - phenosanic acid as an adjunct therapy in patients with focal epilepsy.

Material And Methods: A randomized, double-blind, placebo-controlled, parallel-group study evaluated the efficacy and safety of phenosanic acid as an adjunct therapy to basic antiepileptic drugs in 120 patients with focal epilepsy. Primary purpose: to study the dynamic of seizure frequency.

Multiarm Star-Shaped Polydimethylsiloxanes with a Dendritic Branching Center.

New multiarm stars have been synthesized based on polylithium derivatives of high-generation carbosilane dendrimers. In the synthesis of multiarm stars based on the eighth-generation dendrimer, steric hindrances were observed even during the synthesis of a polylithium initiator. Subsequently, this led to chain transfer reactions between growing arms, as well as other side effects.

The self-diffusion of polymethylsilsesquioxane (PMSSO) dendrimers in diluted solutions and melts.

Recently developed non-functional derivatives of polymethylsilsesquioxane (PMSSO) dendrimers of the first to fifth generation were characterized by 1H, 13C and 29Si NMR spectroscopy. The self-diffusion and NMR relaxation of PMSSO dendrimers in dilute solutions of toluene and melts were investigated in a wide temperature range (-50-80 °C). The hydrodynamic radii of dendrimers were determined from the self-diffusion coefficients measured in diluted solutions according to the Stokes-Einstein equation.

H NMR in a quasi-one-dimensional zig-zag spin chain of hambergite, BeBO(OH).

One-dimensional spin chains are important testbeds for the investigation of quantum many-body systems. Here, we introduce a new quasi-one-dimensional chain of spin-1/2 H nuclei in hambergite (BeBO(OH)) crystal. The distinctive feature of hambergite is the zig-zag arrangement of the spins in the chains compared to the systems reported earlier.

[Use of Detravenol in treatment of chronic venous insufficiency of lower limbs].

Aim: The purpose of this study was to prove that Detravenol is not inferior by clinical efficacy to Detralex® in the course administration in patients presenting with chronic venous insufficiency of the lower extremities caused by lower limb varicose veins.

Patients And Methods: Ours was a prospective randomized open-liable comparative trial aimed at determining efficacy and safety of the two drugs in parallel groups with active control. The trial enrolled a total of 106 patients with chronic venous insufficiency of the lower extremities secondary to lower limb varicose veins.

Evaluation of Stromal Vascular Fraction Properties and Histological Changes of Regenerating Tissue during Healing of Radiation-Induced Lesions in the Rectum.

We analyzed the main properties of autologous adipose-derived stromal vascular fraction (SVF) used for the treatment of radiation-induced lesions in the rectum. No statistically significant correlation between the main characteristics of the cell product (cell number, viability) and patient's age or donor area were revealed. The stages and peculiarities of histological changes in the regenerating tissue after injection of autologous adipose tissue cells were analyzed.

Orientational dependencies of dynamics and relaxation of multiple quantum NMR coherences in one-dimensional systems.

Dynamics and relaxation, or decoherence, of multiple quantum (MQ) coherences are investigated experimentally and theoretically for different orientations of a single crystal of fluorapatite with respect to the external magnetic field. Dynamics of MQ coherences is studied as a function of the preparation period of the MQ NMR experiment. Their relaxation, or decoherence, during the evolution period is also investigated.

Hysteresis-like binding of coagulation factors X/Xa to procoagulant activated platelets and phospholipids results from multistep association and membrane-dependent multimerization.

Binding of coagulation factors X (fX) and Xa (fXa) to activated platelets is required for the formation of membrane-dependent enzymatic complexes of intrinsic tenase and prothrombinase. We carried out an in-depth characterization of fX/fXa binding to phospholipids and gel-filtered, thrombin-activated platelets. Flow cytometry, surface plasmon resonance, and computational modeling were used to investigate interactions of fX/fXa with the membranes.

EXPERIENCE OF APPLICATION OF VOLUME FORMING AGENT «DAM+» IN TREATMENT OF ANAL INCONTINENCE ASSOCIATED WITH INCOMPETENCE AND TRAUMA OF ANAL SPHINCTER.

The attempts of introduction of volume forming agent in submucous layer started at the beginning of 1990th. The aim of these innovations was to rise of basal pressure. This research has been performing since 2007.

[Methylation status of line-1 retrotransposon in chromosomal mosaicism during the early stages of human embryonic development].

Early stages of human embryonic development are characterized by spatio-temporal coincidence of events of total epigenetic genome reprogramming and elevated level of mosaic forms of numerical chromosome abnormalities. It is possible that the abnormal reprogramming of various regions of the genome can lead to violations of local epigenetic chromatin organization and gene expression, affecting the correct chromosome segregation during mitosis. In this study, a comparative analysis of the methylation index of LINE-1 retrotransposon, which is largely reflecting the methylation profile of the genome, is performed in placental tissues of spontaneous abortions with complete and mosaic forms of aneuploidy, and with a normal karyotype, as well as in the control group of induced abortions of the first trimester of pregnancy.

[Hypercoagulation syndrome in multiple myeloma].

Aim: To determine the frequency and pattern of blood clotting disorders in patients with multiple myeloma (MM) and to evaluate the adequacy of preventive anticoagulant or antiaggregant therapy.

Subjects And Methods: The prospective study conducted at the Department for High-Dose Chemotherapy and Bone Marrow Transplantation, Hematology Research Center, Ministry of Health of the Russian Federation, in March 2012 to May 2013, enrolled 25 patients (13 men and 12 women) aged 29-72 years (median age 54 years) with new-onset MM. The latter was staged using the Durie-Salmon classification: Stages I, II, and III were determined in 2, 10, and 13 patients, respectively.

[Characteristics of perioperative period in Xenon-based combined general anaesthesia in neurosurgery].

Neuroprotection could be the aim to use Xenon for general anesthesia. However the experience of Xenon anesthesia in neurosurgery is quite limited. The appraisal of Xenon based anesthesia was accomplished in 12 patients during various brain surgery.

[The use of remaxol in combined intensive therapy of acute mushroom poisoning].

A case of very severe mushroom poisoning is reported. Traditional hepatoprotective therapy with ademethionine, ornithine-aspartate, and essential phospholipids failed to ensure positive dynamics of the hepatic and general functional state. Hepatic insufficiency was complicated by cerebral oedema and swelling, bilateral pneumonia, and acute respiratory distress of mixed genesis.

[The phenomenon of vascular microthrombosis in mucoperichondrium associated with plastic closure of nasal septum perforations].

The objective of the present study was to identify specific hematological features characterizing the pathophysological processes of clinical significance associated with plastic closure of nasal septum perforations. Changes of clinical, biochemical, and coagulation-related blood characteristics developing as a result of the surgical treatment of the patients with ENT pathology were analysed. It was shown that D-dimer is a specific hematological characteristic that reflects the phenomenon of postoperative vascular microthrombosis in mucoperichondrial-periosteal flaps associated with plastic closure of nasal septum perforations.

A Solid-State NMR Investigation of MQ Silicone Copolymers.

The structure of MQ copolymers of the general chemical formula [(CH)SiO] [SiO] was characterized by means of solid-state magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy. The MQ copolymers are highly branched polycyclic compounds (densely cross-linked nanosized networks). MQ copolymers were prepared by hydrolytic polycondensation in active medium.

[The ways of improvement of direct results of surgery of patients with rectal cancer].

The data of 1740 patients (during 20 years) with rectal cancer were analyzed. Planned operations were performed in 95.8% of patients.

[Correction of metabolic disorders during treatment of alcohol-induced liver injuries in patients with acute alcoholic intoxication].

A total of 103 patients with acute alcoholic intoxication were examined and treated for alcohol-induced hepatic lesions. It was shown that remaxol reduced severity of metabolic disorders associated with hypoxic conditions and active lipid peroxidation and thereby decreased the frequency of alcoholic delirium to 10.8% (n=7) compared with ademetionine (10.

[Cryodestruction in neurosurgery].

The study aimed to work out the method of cryodestruction of brain tumors. 10 patients with neuroepithelial brain tumors were prospectively operated on with the use of cryodestruction. MRI was performed before and after the operation.

Identification of signal transduction pathways involved in the formation of platelet subpopulations upon activation.

Platelets are formed elements of blood. Upon activation, they externalize phosphatidylserine, thus accelerating membrane-dependent reactions of blood coagulation. Activated platelets form two subpopulations, only one of which expresses phosphatidylserine.

[Rare combination of acromegaly, syringomyelia and Chiari I malformation].

Chiari I Malformation (CM) is a congenital pathology of rombencephalon development characterized by disparity of brain structures and bony compartment in posterior fossa. The incidence of Chiari I malformation ranges from 3.3 to 8.