Publications by authors named "Vashti Edosuyi"
Bratisl Lek Listy
January 2023
Article Synopsis
- Malate, a compound in the TCA cycle, was studied for its potential to enhance nitric oxide (NO) signaling and protect against kidney damage in rats with obstructive nephropathy.
- In the experiment, rats underwent kidney injury through ureter ligation and were then treated with malate for ten days, showing reduced expression of kidney injury markers and increased NO production in the kidney.
- Results indicated that while malate reduced overall kidney inflammation and injury, it selectively decreased fibrosis in the renal medulla, suggesting its potential therapeutic role in kidney diseases.
