[CLASSIFICATION OF ACUTE PANCREATITIS: CURRENT STATE OF THE ISSUE].

The article analyzed disadvantages of "Atlanta-92" classification of acute pancreatitis and its two modifications: APCWG-2012 and IAP-2011. The school of Saint-Petersburg pancreatologists suggested the classification AP of Russian Surgical Society (2014), which represented the concept of disease staging.

[Ways to improve efficacy of emergency operative interventions in patients with cancer of the left flank of the colon complicated by obstruction].

In order to improve radicalism of emergency surgical interventions an appropriate method of total mesocolonectomy and D3-lymph node dissection in the medial-lateral direction and the principle of "no-touch technique" were used in 14 patients. This technique is safe, effective, does not prolong the duration of operation and postoperative period, is not followed by increased number of complications and lethality.

[Multilayer deep hernioplasty by E. Shouldice method in inguinal hernias].

The article gives a detailed description of steps of performing multilayer deep hernioplasty after E. Shouldice. In order to substantiate the possibilities to perform the procedure the structure of the transverse fascia in the ilioinguinal area was investigated in 20 corpses without hernias as compared with those having hernias.

Histoprotective effect of antihypoxant olifen during experimental acute pancreatitis.

We evaluated the efficiency of perfusion with olifen in preventing oxidative stress at the early stage of acute pancreatitis. Transaortic perfusion with olifen prevented clinical and biochemical symptoms of acute pancreatitis, attenuated oxidative stress, reduced peritoneal exudation, and restricts the area of pancreatic necrosis to 6% tissue.

[Pharmacological analysis of morphofunctional changes in the adrenergic structures of the pancreas as affected by lesions of the endocrine and exocrine pancreas].

The adrenergic section of the vegetative pancreatic innervation has been examined, using morphological, histochemical and biochemical methods, during neurogenic injury, acute experimental pancreatitis and alloxan diabetes. It has been established that the development of those etiologically different processes was accompanied by catecholamine level reduction in the adrenergic structures of the pancreas which can be prevented by ganglioblockers. It is concluded that sympathetic nervous system participates in etiopathogenesis of a number of pancreatic diseases and that it is possible to prevent and treat them with sympathotropic agents.

[Pathogenesis and clinical significance of fat necrosis in acute pancreatitis].

An analysis of results of 200 experiments, 100 autopsies after death from acute destructive pancreatitis and clinical observation of 2000 patients with necrotic forms of acute pancreatitis has given data on pathogenesis of fat necrosis, dynamics of its development, its interrelationships with alterations of the pancreas parenchyma. A concept of unity of proteolytic and steatonecrotic components of acute destructive pancreatitis is substantiated. The authors propose a classification of periods of development of fat necrosis, determine the clinical significance of alterations of the fat tissue at early terms of the disease, give recommendations for the surgical and conservative treatment.

[Prevention and treatment of pulmonary complications in patients with combined injuries of the chest accompanied by shock in the early period of trauma].

Complications were noted in 83% of patients with an associated trauma of the chest. Bilateral pneumonia was the most frequent complication (57.7%), then were traumatic pulmonitis (15.

[Characteristics of the local pathological changes in acute pancreatitis and therapeutic procedural problems].

On the basis of great clinical material (804 patients with pancreatonecrosis) the authors give clinico-morphological characteristics of main components of local pathological changes connected with acute pancreatitis. Debatable questions of the curative methods are described. More exact indications for early surgical interventions are considered in detail.