[Bioorganic chemistry: institutes, journals, publications, a short scientific metric analysis. On the 50th anniversary of the Institute of Natural Compound Chemistry, Institute of Bioorganic Chemistry].

An attempt to illustrate the development of bioorganic chemistry in Russia and all over the world has been made. The development of a new field of science was accompanied by the emergence of specialized journals, organizations, departments and institutions for research in this field. A brief report about the four most important world journals on bioorganic chemistry is represented.

[Inositol-containing sphingolipid from red algae Gracilaria verrucosa].

An unusual polar lipid was isolated from the red alga Gracilaria verrucosa. Inositol, sphingosine bases, fatty acids, and phosphate were identified by GC and GC-MS analysis among the products of its acid methanolysis. On the basis of the lipid composition, chromatographic behavior, chemical properties, and mass spectra, the inositolphosphoceramide structure was proposed for this lipid.

[Effect of the ratio of polyunsaturated fatty acids of the omega 6 and omega 3 families in the diet of rats on the cholesterol content of the blood plasma and liver].

The influence of polyunsaturated fatty acids omega 6 and omega 3 on the cholesterol level in the blood plasma and liver was studied in rats fed with rations containing no fats during 6 weeks. The total cholesterol content in the blood plasma decreased in the animals given ration with eicosapentaenoic acid (EPA), and the ration containing "Iwashi" sardine fat combined with sunflower oil. In the animals receiving the latter ration the level of free cholesterol in the liver lowered, however, the level of total cholesterol and its esters rose that could be explained by the reduction of the ratio of fatty acids 20:4/18:2 in cholesterol esters.

[Detection of N-acylethanolamine phospholipids in neuroblastoma C1300 cells].

Phospholipids with high chromatographic mobility are detected in cells of murine neuroblastoma C 1300. One of them is identified (proceeding from data of successive chemical degradation) as N-acylphosphatidylethanolamine. It may be a precursor of physiologically active N-acylethanolamines.

[A non-destructive sensitive reagent for lipid detection on TLC plates].

The aqueous solutions of 3 acidic and 14 basic dyes used as reagents for detection of lipids without their destruction are tested on plates for highly effective TLCh with the silicagel layer fixed by the silicic acid sol. It is shown that 0.002% solution of basic fuchsin in 1% boric acid reveals neutral, phospho- and glycolipids with the sensitivity compared with such in detection of sulphuric acid.