Publications by authors named "Varvara Yu Chirkova"
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Synopsis of recent research by authors named "Varvara Yu Chirkova"
- Varvara Yu Chirkova's recent research primarily focuses on the development and evaluation of new antiviral agents, specifically targeting the main protease of SARS-CoV-2, through the synthesis of various chemical compounds, including thiazolo-thiophenes and triterpenic acid amides.
- Her findings suggest that several synthesized derivatives, particularly those based on usnic acid, exhibit moderate inhibitory activity against the SARS-CoV-2 main protease, indicating their potential as effective therapeutic agents against coronavirus infections.
- Chirkova's work also highlights ongoing challenges in the production of soluble recombinant proteins and underscores the importance of molecular modeling in predicting the binding capability of these compounds, emphasizing the relevance of this research in the context of current and future antiviral drug design.
