Assessment of functional outcome of patients undergoing surgery for chronic pancreatitis: A prospective study.

Backgrounds/aims: This study was done with the aim of assessing impact of surgery for chronic pancreatitis on exocrine and endocrine functions, quality of life and pain relief of patients.

Methods: 35 patients of chronic pancreatitis who underwent surgery were included. Exocrine function assessed with fecal fat globule estimation and endocrine function assessed with glycated haemoglobin (HbA1C), fasting plasma glucose (FPG), Insulin and C-peptide levels.

Solubility enhancement effect at absorption site on bioavailability of ritonavir using liquisolid technique.

The present study revolved around determining the effect of increase in the solubility of these drugs at the absorption site using ritonavir as a drug model. Ritonavir per-oral tablets were prepared using versatile and nonionic surfactants having high solubilization rate, which were further marked with high rate of dissolution. The high rate of dissolution formula applied to the solid state characterization by means of transition electron microscopy, differential scanning calorimetry, scanning electron microscopy, X-ray diffraction and infrared spectroscopy.