Multiproxy paleoclimate dataset from the Bednikund alpine lake in the Central Himalaya.

We describe here a multiproxy dataset (grain size, environmental magnetism, stable carbon isotope, total nitrogen, and total organic carbon) generated on a ~116 cm long trench profile from the high altitude alpine Badnikund lake in the Central Himalaya. The dataset also includes environmental magnetic and organic geochemistry data on catchment soils of the Bednikund lake. The presented data is related to the research article "Middle Holocene Indian summer monsoon variability and its impact on cultural changes in the Indian subcontinent" [1].

Clofazimine enhances the efficacy of BCG revaccination via stem cell-like memory T cells.

Tuberculosis (TB) is one of the deadliest diseases, claiming ~2 million deaths annually worldwide. The majority of people in TB endemic regions are vaccinated with Bacillus Calmette Guerin (BCG), which is the only usable vaccine available. BCG is efficacious against meningeal and disseminated TB in children, but protective responses are relatively short-lived and fail to protect against adult pulmonary TB.

Diagnostic Potential of Recombinant scFv Antibodies Generated Against Hemagglutinin Protein of Influenza A Virus.

Human influenza A viruses have been the cause of enormous socio-economic losses worldwide. In order to combat such a notorious pathogen, hemagglutinin protein (HA) has been a preferred target for generation of neutralizing-antibodies as potent therapeutic/diagnostic agents. In the present study, recombinant anti-HA single chain variable fragment antibodies were constructed using the phage-display technology to aid in diagnosis and treatment of human influenza A virus infections.