Publications by authors named "Varsha Radhakrishnan"

Article Synopsis
  • Delirium is a complex syndrome marked by changes in attention and awareness, often accompanied by sleep issues like circadian rhythm inversion and sleep fragmentation.
  • There are currently no FDA-approved drugs specifically for delirium or its associated sleep disturbances; management mainly involves treating underlying medical problems and promoting proper sleep patterns through non-drug approaches.
  • Some medications like ramelteon, melatonin, dexmedetomidine, and dual orexin receptor antagonists show promise in helping manage these sleep disruptions, particularly in ICU patients, although their evidence of effectiveness varies.
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Background: Burnout interventions are limited by low use. Understanding resident physician preferences for burnout interventions may increase utilization and improve the assessment of these interventions.

Objective: This study aims to use an econometric best-worst scaling (BWS) framework to survey internal medicine resident physicians to establish help-seeking preferences for burnout and barriers to using wellness supports by quantifying selections for 7 wellness support options and 7 barriers.

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This study evaluated the efficacy of a collaborative intervention between hospitals and universities to decrease the length of stay (LOS) in the Emergency Department (ED) for college students. The hypothesis was that university collateral would decrease LOS in the ED. A retrospective chart review was performed for 834 consults in patients aged 18-25 regarding presence of collateral, disposition, and LOS.

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Background: The effects of gender, headaches, and their interaction on sleep health (sleep duration, sleep onset and continuity, and indications of hypersomnolence) have not been well studied.

Materials And Methods: For American adolescents, we contrasted sleep health variables between males (n = 378) and females (n = 372) and between individuals with chronic headaches (n = 102 females and 60 males) and without chronic headaches (n = 270 females and 318 males) using data from surveys.

Results: Not all measures of sleep health differed between groups, but the following patterns were observed for the measures that did differ.

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Aim: We tested for associations of bedtime, sleep duration, instant messaging, and chronic headaches with hypersomnolence and academic performance in a sample of high school students in New Jersey, USA.

Methods: Students were surveyed anonymously and asked to report their sleep and messaging habits, headache status, and overall grades.

Results: We found that greater hypersomnolence was associated with later bedtimes, shorter sleep durations, and the presence of chronic headaches, but not with messaging after lights out.

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Background: In bluegill sunfish, the melanin-containing pigment granules of the retinal pigment epithelium undergo cyclic movements in response both to ambient lighting and circadian cues. Pigment granules aggregate into the cell body at night (in the dark), and disperse into apical processes during the day (in the light). Regulation of pigment granule aggregation in a number of fishes depends on modulating the intracellular levels of cyclic adenosine monophosphate.

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