Publications by authors named "Varinder Singh Bedi"
Article Synopsis
- Chronic Limb Threatening Ischemia (CLTI) is a severe condition leading to high rates of limb amputation and cardiovascular death, particularly in cases where standard treatments fail.
- Endovascular interventions are the main treatment strategy, but a significant number of patients are considered "no-option," prompting interest in new therapies like bone marrow-derived mesenchymal stromal cells (BM-MSC).
- REGENACIP is an approved BM-MSC therapy in India for patients with critical limb ischemia who are not candidates for traditional revascularization, and this review discusses its potential benefits and effectiveness in treating CLTI.
Peripheral arterial disease (PAD) affects 12 % of adult population and is increasing globally and in India. Peripheral arterial disease when associated with atherosclerosis in two or more other arterial beds such as coronary artery disease (CAD), mesenteric/renal artery and cerebrovascular disease (CVD), is known as polyvascular disease. The Reduction of Atherothrombosis for Continued Health (REACH) registry reported that 1 out of 6 patients had multi-vascular bed involvement.
View Article and Find Full Text PDFCarotid artery stenosis: stroke prevention procedure-indications, controversies, and challenges.
Indian J Thorac Cardiovasc Surg
January 2024
Medical therapy versus TEVAR for uncomplicated type B aortic dissection.
Indian J Thorac Cardiovasc Surg
June 2019
The standard of care in uncomplicated acute type B aortic dissection (uTBAD) has been optimal medical management. Surgical repair and endovascular interventions are adjuncts in managing complicated type B dissection. Increasing safety and confidence in the thoracic endovascular aortic repair (TEVAR) and recent data indicating long-term complications in medical management of uTBAD has brought a shift in treatment approach.
View Article and Find Full Text PDFContext And Objective: venous thrombosis occurs as a result of interaction of genetic and acquired factors including activated protein C resistance (APC-R), fibrinogen levels, antithrombin, protein C, protein S, lupus anticoagulants and anticardiolipin antibodies. This study was aimed at determining the prevalence of these common thrombophilia markers in Asian Indians with primary venous thrombosis.
Design And Setting: this was a cross-sectional study carried out in Mumbai.