Exploring the role of the MUC1 mucin in human oral lubrication by tribological in vitro studies.

In the context of the oral cavity, an organic layer known as the mucosal pellicle (MP) adheres to the surface of the oral epithelium, playing a pivotal role in lubricating and safeguarding oral tissues. The formation of the MP is driven by interactions between a transmembrane mucin known as MUC1, located on the oral epithelium, and salivary secreted mucin, namely MUC5B and MUC7. This study aimed to investigate the function of MUC1 and the influence of its structure on MP lubrication properties.

Coupling tensile test with LC-OCT and ultrasound imaging: investigation of the skin sublayers mechanical behaviour.

The skin is an envelope that covers the entire body. Nowadays, understanding and studying the mechanical, biological and sensory properties of the skin is essential, especially in dermatology and cosmetology. The in-depth study of the skin's mechanical behaviour is a highly intriguing challenge, enabling the differentiation of the behaviour of each layer.

Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves.

The ensuing pilot investigation sheds new light on characterizing tumoral and non-tumoral human skin mechanical properties that will not only assist the dermatologist's diagnosis but also could constitute the creation of an Artificial Intelligence database for upcoming research. A modern, non-invasive, and contact-free methodology-UNDERSKIN-was developed, and hinges upon Fourier transform computations that permit the analysis of surface wave dispersion with a specific skin inversion model and viscoelastic model. It yields a detailed look at how particle movements of the medium propagate throughout its near sub-surface, hence a novel knowledge of the mechanical responses of skin tumors.

Perspectives on Astringency Sensation: An Alternative Hypothesis on the Molecular Origin of Astringency.

Flavor is one of the main drivers of food consumption and acceptability. It is associated with pleasure feels during eating. Flavor is a multimodal perception corresponding to the functional integration of information from the chemical senses: olfaction, gustation, and nasal and oral somatosensory inputs.

Static and active tactile perception and touch anisotropy: aging and gender effect.

Although the human finger is the interface used for the touch process, very few studies have used its properties to provide a description of tactile perception regarding age and gender effects. Age and gender effects on the biophysical properties of the human finger were the main topics of our previous study. Correlating tactile perception with each parameter proved very complex.

Impact of finger biophysical properties on touch gestures and tactile perception: Aging and gender effects.

The human finger plays an extremely important role in tactile perception, but little is known about the role of its biophysical properties (mechanical properties, contact properties and surface topography) in tactile perception. In addition, the touch gestures used to perceive an object's properties differ among people. We combined studies on the biophysical properties and the vibrations measured from the human finger to understand the age and gender effects on the tactile perception and the difference between the touch gestures.

Biomechanical Characterization of Intracranial Aneurysm Wall: A Multiscale Study.

Objective: Aneurysm wall biomechanics are not yet an integral part of aneurysm rupture risk evaluation. We aimed to develop a new technique describing the biomechanical properties of aneurysm wall and correlating them to rupture status.

Methods: Aneurysm wall samples collected during surgery were submitted before and after freezing to tensile tests or as fresh samples to indentation tests.

Biophysical properties of the human finger for touch comprehension: influences of ageing and gender.

The human finger plays an extremely important role in tactile perception, but little is known about how age and gender affect its biophysical properties and their role in tactile perception. We combined studies on contact characteristics, mechanical properties and surface topography to understand age and gender effects on the human finger. The values obtained regarding contact characteristics (i.

Study of the tactile perception of bathroom tissues: Comparison between the sensory evaluation by a handfeel panel and a tribo-acoustic artificial finger.

Tactile perception is one of the sensorial modes most stimulated by our daily environment. In particular, perceived softness is an important parameter for judging the sensory quality of surfaces and fabrics. Unfortunately, its assessment greatly depends on the tactile sense of each person, which in turn depends on many factors.

In vivo skin biophysical behaviour and surface topography as a function of ageing.

Normal skin ageing is characterised by an alteration of the underlying connective tissue with measurable consequences on global skin biophysical properties. The cutis laxa syndrome, a rare genetic disorder, is considered as an accelerated ageing process since patients appear prematurely aged due to alterations of dermal elastic fibres. In the present study, we compared the topography and the biomechanical parameters of normal aged skin with an 17 year old cutis laxa patient.

Characterization of the mechanical properties of a dermal equivalent compared with human skin in vivo by indentation and static friction tests.

Background/aims: The study of changes in skin structure with age is becoming all the more important with the increase in life. The atrophy that occurs during aging is accompanied by more profound changes, with a loss of organization within the elastic collagen network and alterations in the basal elements. The aim of this study is to present a method to determine the mechanical properties of total human skin in vivo compared with dermal equivalents (DEs) using indentation and static friction tests.

A new approach to describe the skin surface physical properties in vivo.

In the present paper, we describe a new mechanical method characterising the physico-chemical properties of human skin and their variations along with liquid exposure scenario to the skin surface. A specific bio-tribometer has been developed to study the physical properties of the skin in vivo by measuring the maximum adhesion force between the skin and the bio-tribometer. We showed that the lipidic film present on skin surface was responsible for skin adhesion due to capillary phenomena.