Publications by authors named "Vargas V"

Background: Bibliometric analyses are a proficient method for understanding the dynamics of publications. Unstable thoracolumbar injuries are a prevalent topic in neurosurgery and orthopedic research.

Methodology: Web of Science was searched for the 100 most-cited articles on unstable thoracolumbar injuries.

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Background: Acute kidney injury (AKI) is a serious complication of cirrhosis. A systematic, global characterisation of AKI occurring in patients with cirrhosis is lacking. We therefore aimed to assess global differences in the characteristics, management, and outcomes of AKI in hospitalised patients with cirrhosis.

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Background And Aims: Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance because SI is a driver of the most severe forms of ADC, including acute-on-chronic liver failure (ACLF). Blood biomarkers of SI already evaluated in ADC failed to appropriately assess SI in ADC. We aimed to investigate whether gene expression related to circulating immune cells could quantify SI in ADC.

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(1) Background: Alcohol and/or other drug use problems (ADUPs) and trauma are key risk factors for intimate partner violence (IPV) that should be addressed in perpetrator programs. Participants with ADUPs and trauma histories may display greater difficulties in emotion regulation, which may increase the likelihood of IPV recidivism. The study aimed to examine differences among participants with trauma, ADUPs, ADUPs and trauma, and without such factors in dropout, IPV, and variables related to emotion regulation at pre- and post-intervention; (2) Methods: A sample of 312 men court-mandated to attend a perpetrator program (Contexto Program) was used.

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Background: A National Registry for Wilson disease (WD) was recently started by the Spanish Association for Study of the Liver (AEEH). We evaluated the genetic data of the patients and the differences between regions and hospitals.

Method: Multicentric observational study from the WD Registry after the first year.

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Importance: There are no useful treatments to prevent the development of severe complications of liver cirrhosis. Simvastatin and rifaximin have shown beneficial effects in liver cirrhosis.

Objective: To assess whether simvastatin combined with rifaximin improves outcomes in patients with decompensated cirrhosis.

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Phosphorylation of connexin 43 (Cx43) is an important regulatory mechanism of gap junction (GJ) function. Cx43 is modified by several kinases on over 15 sites within its ∼140 amino acid-long C-terminus (CT). Phosphorylation of Cx43CT on S255, S262, S279, and S282 by ERK has been widely documented in several cell lines, by many investigators.

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The aim of this prospective case-control study was to describe and implement a reliable, accurate, and straightforward ultrasound-guided proximo-medial approach technique for injecting the carpal flexor tendon sheath in horses. The proximo-medial ultrasound-guided approach for intrathecal access to the carpal canal, as described in this study, was firstly developed on ten cadaveric limbs using an undiluted ionic iodinated contrast medium. Landmarks were identified, and the access point was established.

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Bacterial infections (BI) are a major cause of mortality in patients with alcohol-associated hepatitis (AH); however, only a few studies have investigated BI in AH in the last decade. Therefore, we aimed to assess the features and outcomes of BI in patients with AH. This observational descriptive study included patients with AH admitted to a tertiary academic hospital between 2016 and 2021.

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In early 2024, explosive outbreaks of Oropouche virus (OROV) linked to a novel lineage were documented in the Amazon Region of Brazil. We report the introduction of this lineage into Colombia and its co-circulation with another OROV lineage. Continued surveillance is needed to prevent further spread of OROV in the Americas.

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Article Synopsis
  • * Stereotactic radiosurgery (SRS) is emerging as a potential treatment for patients with recurrent or leftover NFPAs, but more research is needed to fully understand its long-term effects.
  • * A systematic review of 24 studies with nearly 3,800 patients found that SRS had a high success rate (approximately 92.3% tumor control) but also showed risks for hormonal deficiencies and visual field problems, highlighting the need for ongoing monitoring after treatment. *
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  • Alcohol-associated hepatitis (AH) has high mortality rates, with up to 40% of patients dying within 6 months, partly due to increased susceptibility to infections that worsen their condition.
  • A study analyzed the immune responses of 36 healthy individuals, 48 patients with alcohol use disorder, and 224 AH patients, finding that abstaining from alcohol boosts antibody responses, while AH patients had reduced antiviral and antibacterial antibodies linked to worse outcomes.
  • The research indicates that a lower level of antiviral antibodies in AH patients can predict liver disease complications and mortality, suggesting that serum viral epitope signatures could be valuable for assessing patient prognosis.
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  • Wilson disease is a genetic disorder affecting copper metabolism, primarily linked to mutations in the ATP7B gene, showing a wide range of clinical symptoms among patients.
  • A study of 260 patients revealed that some common mutations, particularly p.Met645Arg and p.Gly869Arg, are underreported due to their milder symptoms, leading to a higher estimated prevalence than recorded (1:3,785, suggesting over 10,500 potential cases in Spain).
  • The findings indicate that individuals with the p.Met645Arg mutation often have fewer severe symptoms at diagnosis and are more likely to be diagnosed later in life, underscoring the need for increased awareness and early intervention.
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  • A non-wearable fall detection system is proposed using a Raspberry Pi4 and an IR-CUT camera, leveraging deep learning techniques for real-time analysis.
  • The system classifies individuals into five states: fallen, crouching, sitting, standing, and lying down, and it sends alerts through Telegram when a fall is detected.
  • Key performance metrics include accuracy of 94.8% and sensitivity of 93.1%, and the system prioritizes privacy by not recording video footage unless a fall occurs, offering a promising low-cost solution for fall detection, especially in resource-limited settings.
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  • The study investigates the effects of prophylactic antibiotics in patients with alcohol-associated hepatitis (AH) undergoing steroid treatment, focusing on their impact on survival and various complications.
  • A systematic review of six studies involving 510 patients found that prophylactic antibiotics reduced the risk of infections and hepatic encephalopathy (HE) but did not significantly improve 90-day survival rates or prevent acute kidney injury (AKI).
  • The findings suggest that while prophylactic antibiotics can reduce certain risks, more extensive research is needed as the sample size required to establish a survival benefit is much larger than the studies reviewed.
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Unlabelled: With the increasing rate of infections caused by multidrug-resistant organisms (MDRO), selecting appropriate empiric antibiotics has become challenging. We aimed to develop and externally validate a model for predicting the risk of MDRO infections in patients with cirrhosis.

Methods: We included patients with cirrhosis and bacterial infections from two prospective studies: a transcontinental study was used for model development and internal validation (n = 1302), and a study from Argentina and Uruguay was used for external validation (n = 472).

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Background: Alcohol-associated hepatitis (AH) is associated with significant mortality. Model for End-Stage Liver Disease (MELD) score is used to predict short-term mortality and aid in treatment decisions. MELD is frequently updated in the course of AH.

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Background: In recent years, the aesthetic market has become more prominent for being not only a tool to correct unwanted features but also a social means for improving quality of life. The use of 30% polymethylmethacrylate (PMMA) as a gluteal filler has grown in popularity all over the world, being sought after by men and women for body remodeling because it provides a natural look as well as significant long-lasting results.

Methods: A retrospective, multicenter study analyzed the medical records of 2801 patients who underwent a total of 4725 gluteal filler procedures between January 2009 and December 2021 at the different locations of Clínica Leger.

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  • Mayaro Fever (MF) is caused by the Mayaro virus and has been reported in outbreaks in Latin America, particularly in Leticia, Colombia, where a fever surveillance study was conducted.
  • In a sample of 1,460 patients, most cases were linked to dengue and malaria, but 71.4% were unexplained until metagenomic sequencing detected MAYV in two patients with MF symptoms.
  • This research marks the first identification of MAYV in Colombia, indicating a need for more studies and improved surveillance to monitor its spread in the region.
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Aҫai fruit is characterized by the properties of its bioactive compounds; however, this fruit is highly perishable and its compounds are sensitive when exposed to non-optimal environmental factors. Therefore, the objective of this study was to encapsulate the fruit pulp by spray drying to improve the nutritional value and extend the shelf life of the products derived from acai fruit. Maltodextrin was used as a wall material and the process was optimized to obtain the desirable values of the response variables.

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Introduction: Even though certain technical limitations associated with the small size of the patients were taken for granted in the advent of pediatric robotic surgery, we could now be facing a paradigm shift challenging these old beliefs.

Materials And Methods: A retrospective study of patients undergoing Da-Vinci-Xi(IS4000)-assisted urological surgery from May 2022 to October 2023 was carried out. Patients were divided into two groups -Group A < 15 kg and Group B ≥ 15 kg.

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Objective: Patients with alcohol-associated hepatitis (AH) have a high mortality. Alcohol exacerbates liver damage by inducing gut dysbiosis, bacterial translocation and inflammation, which is characterised by increased numbers of circulating and hepatic neutrophils.

Design: In this study, we performed tandem mass tag (TMT) proteomics to analyse proteins in the faeces of controls (n=19), patients with alcohol-use disorder (AUD; n=20) and AH (n=80) from a multicentre cohort (InTeam).

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Correction for 'Photoluminescence modification of europium(III)-doped MAlO (M = Zn, Mg) spinels induced by Ag@SiO core-shell nanoparticles' by Rodrigo A. Valenzuela-Fernández , , 2024, https://doi.org/10.

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In recent years, there has been an increasing interest in developing new inorganic compounds with exceptional properties for advanced materials. Specifically, compounds containing europium have attracted much attention due to their luminescent properties. These compounds are used in electronics, biotechnology, medicine, and catalysis.

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Frailty and sarcopenia are well-recognized factors related to worse outcomes in patients with cirrhosis, including liver transplant (LT) candidates. Implications of pre-LT functional and muscle deterioration also affect post-LT outcomes. Patients with cirrhosis and acute-on-chronic liver failure (ACLF) have a lower survival rate, both before and after LT.

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