Development of Antioxidant-Active Sericin-Curcumin-Loaded Sodium Alginate/Polyvinyl Alcohol Films Crosslinked with Calcium Chloride as a Promising Wound Dressing Application.

Silk sericin (SS) and curcumin (Cur) possess significant antioxidant properties, making them highly beneficial for wound healing applications. This study aimed to develop SS-Cur-loaded sodium alginate/polyvinyl alcohol (SA/PVA) films crosslinked with calcium chloride, creating a biomaterial with enhanced stability and antioxidant properties. Wound dressings containing SS-Cur were fabricated by mixing SA and PVA at different ratios of 1:1, 1:2, 1:4, and 1:6.