Publications by authors named "Vardhil Gandhi"

Objective: To assess the effects of tranexamic acid (TXA) in individuals with kidney stones undergoing percutaneous nephrolithotomy (PCNL).

Patients And Methods: We performed a literature search of Cochrane Library, PubMed (including MEDLINE), Embase, Scopus, Global Index Medicus, trials registries, grey literature, and conference proceedings. We included randomised controlled trials (RCTs) that compared treatment with PCNL with administration of TXA to placebo (or no TXA) for patients aged ≥18 years.

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Article Synopsis
  • Percutaneous nephrolithotomy (PCNL) is the preferred method for treating large kidney stones, but it has a higher risk of bleeding compared to other treatments like ureteroscopy and shock wave lithotripsy.
  • Tranexamic acid (TXA) is tested in this context as a potential solution to reduce bleeding in patients undergoing PCNL.
  • The study reviewed data from 10 randomized controlled trials, involving 1,883 participants, focusing on outcomes such as blood transfusions, stone-free rates, and complications related to the use of TXA during the procedure.
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Purpose: Gender equity is a key performance metric in research, including systematic reviews, and is increasingly noted in publications. We performed this study to assess gender parity in scientific authorship of systematic reviews published in the urological literature.

Materials And Methods: We identified all published systematic reviews addressing questions of therapy/prevention in 5 major urological journals (®, , , , and ) from 1998 to 2021.

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Objective: Investigate neurodevelopmental outcomes at 3 years corrected age in infants with a birth weight ≤1250 g born to single parents.

Study Design: Infants born between 1995 and 2010 with a birth weight ≤1250 g were considered eligible. Primary outcome was neurodevelopmental impairment; considered present if a child had any of the following: cerebral palsy, cognitive delay, visual impairment, or deafness/neurosensory hearing impairment.

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