Kleine-Levin syndrome related to pregnancy: a case report.

Unlabelled: Kleine-Levin syndrome (KLS) is a rare disorder of recurrent hypersomnolence. The pathophysiology continues to be poorly understood. Autoimmunity, genetic polymorphisms, dysfunction of the hypothalamic axis, and abnormalities in functional imaging have been proposed.

Synthesis and Stereochemical Assignment of Conioidine A: DNA- and HSA-Binding Studies of the Four Diastereomers.

Conioidine A (), isolated in 1993 with unknown relative and absolute configuration, was suggested to be a DNA-binding compound by an indirect technique. Four stereoisomers of conioidine A have been synthesized from d- and l-proline, and the natural product has been identified as possessing (4,6) absolute configuration. Binding of the conioidine diastereomers to calf thymus DNA (CT DNA) and human serum albumin (HSA) has been investigated by fluorescence spectroscopy and isothermal titration calorimetry (ITC).

[Impact of sleep disorders on quality of life in epilepsy].

Objective: To study the relationship between sleep disorder symptoms and health-related quality of life (HRQOL) in patients with epilepsy.

Material And Methods: Three groups of participants were included: patients with epilepsy (EG, =151), healthy controls (CG, =130), patients with a confirmed diagnosis of sleep disorder (SDG, =69). HRQOL was assessed with SF-36 containing 8-domains (D1-D8).

Duration and frequency of drainage and flooding events interactively affect soil biogeochemistry and N flux in subtropical peat soils.

With the demand for restoration and future prediction of climate change effects, subtropical peatlands are expected to be subjected to hydrologic regimes with variable duration and frequency of drained and flooded conditions, but knowledge of their interactive effects on soil biogeochemistry and emission of greenhouse gases including nitrous oxide (NO) is largely limited. The objective of this study was to investigate how the duration and frequency of drainage and flooding events interactively influence soil biogeochemical properties and denitrification and related net NO production rates following rewetting. Surface soils are susceptible to different hydrologic regimes.

Soil phosphorus forms and storage in stormwater treatment areas of the Everglades: Influence of vegetation and nutrient loading.

Stormwater treatment areas (STAs) are an integral component of the Everglades restoration strategies to reduce phosphorus (P) loads from adjacent agricultural and urban areas. The overall objective of this study was to determine the forms and distribution of P in floc and soils along the flow-path of two parallel flow-ways (FWs) in STA-2 with emergent aquatic vegetation (EAV) and submerged aquatic vegetation (SAV), respectively, to assess their stability and potential for long term storage. In EAV high organic matter accretion supported low bulk density and high P concentrations in floc and soil, while high mineral matter accretion in SAV resulted in high bulk density and low P concentrations.

Influence of flow on phosphorus-dynamics and particle size in agricultural drainage ditch sediments.

Particle size is one factor affecting phosphorus (P) dynamics in soils and sediments. This study investigated how flow facilitated by hydraulic pumps and aquatic vegetation species water lettuce (Pistia stratiotes) and water hyacinth (Eichhornia crassipes) affected particle size and P-dynamics in organic sediments in agricultural drainage ditches. Sediments with finer particle size (>0.

Total Synthesis of Alvaradoins E and F, Uveoside, and 10-epi-Uveoside.

Concise total syntheses of the anthracenone -glycosides alvaradoins E and F, uveoside, and 10-epi-uveoside (-) have been accomplished from chrysophanic acid and bromosugar . Key steps in the syntheses include the DBU-induced coupling of and to produce β--glycoside , and a Pb(OAc)-mediated Kochi reaction to introduce the C-1' oxygen atom of the natural products. Isothermal titration calorimetry and fluorescence binding studies reveal that compounds and have good affinity for the plasma protein HSA.

Influence of select bioenergy by-products on soil carbon and microbial activity: A laboratory study.

Concerns about the negative impacts of crop biomass removal on soil ecological functions have led to questioning the long-term sustainability of bioenergy production. To offset this potential negative impact, use of organic C rich by-products from the bioenergy industries have been proposed as a means to replenish soil C in degraded soils. However, the impact of these by-products application on soil carbon dynamics is not fully understood.

Essential medicines for children in Armenia.

Background: Drug therapy plays a key role in pediatrics. Effective treatment in pediatric practice means that medicines should be both effective and safe for children. However, there is not enough data on effectiveness and safety of medicines for children due to small number of clinical trials [1].

Detoxification of toxic heavy metals by marine bacteria highly resistant to mercury.

Pollution in industrial areas is a serious environmental concern, and interest in bacterial resistance to heavy metals is of practical significance. Mercury (Hg), Cadmium (Cd), and lead (Pb) are known to cause damage to living organisms, including human beings. Several marine bacteria highly resistant to mercury (BHRM) capable of growing at 25 ppm (mg L(-1)) or higher concentrations of mercury were tested during this study to evaluate their potential to detoxify Cd and Pb.

Studies on heavy metal accumulation in aquatic macrophytes from Sevan (Armenia) and Carambolim (India) lake systems.

Aquatic macrophytes are unchangeable biological filters and they carry out purification of the water bodies by accumulating dissolved metals and toxins in their tissue. In view of their potential to entrap several toxic heavy metals, 45 macrophytes belonging to 8 families collected from two different physiographic locations (36 from Sevan Lake, Armenia; 9 from Carambolim Lake, Old Goa, India) were studied for estimation of 14 heavy metals. The study was aimed at understanding the importance of these macrophytes in accumulation of toxic metals and controlling the heavy metal pollution and suggesting the remedial measures, if any, for the preservation and restoration of lake ecosystem.