Publications by authors named "Vanna Cavassa"
Article Synopsis
- Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder often seen alongside ADHD, where behavioral therapy is the primary treatment, but medication may also be necessary for severe symptoms like agitation.
- Intravenous valproate (IV-VPA) has shown promise in treating agitation in patients with ASD, potentially offering a safer alternative to conventional medications, although it is not yet widely approved for this use.
- A case study of an 11-year-old boy demonstrated successful treatment with IV-VPA after first-line approaches failed, reinforcing the potential benefits and reduced adverse effects associated with this medication based on existing literature.
Introduction: Our single-center case-control study aimed to evaluate the unclear glymphatic system alteration in autism spectrum disorder (ASD) through an innovative neuroimaging tool which allows to segment and quantify perivascular spaces in the white matter (WM-PVS) with filtering of non-structured noise and increase of the contrast-ratio between perivascular spaces and the surrounding parenchyma.
Methods: Briefly, files of 65 ASD and 71 control patients were studied. We considered: ASD type, diagnosis and severity level and comorbidities (i.