Publications by authors named "Vanja Karlovic-Beslic"
Background: Thyroid dysfunction includes hyper- and hypofunction of the thyroid gland (hyperthyroidism and hypothyroidism). The spectrum encompasses both subclinical and clinical disease presentation. The etiology is vast and varied, as are the risk factors and simptoms.
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- Polyglandular autoimmune syndrome type III (PAS III) is characterized by the combination of type 1 diabetes and autoimmune thyroid disease, prompting research on genetic factors involved.
- The study involved 50 patients, analyzing their CTLA-4 gene polymorphism (rs231775) to determine its connection to PAS III and its clinical severity.
- Results highlighted a significant association between the rs231775 polymorphism and both the occurrence of PAS III and its clinical severity, suggesting that CTLA-4 plays an important role in regulating immune responses.
Background: IDegLira( fixed combination of GLP 1 receptor agonist and insulin) has been shown to be effective in improving the glucoregulation in patients previously treated with oral therapy as well as individual components, GLP-1 receptor agonist or basal insulin.
Objective: The aim of this study is to examine the parameters of metabolic control in patients treated with IDegLira who were previously treated with premix insulin in several daily doses and to compare them with patients whose premix insulin dose was increased.
Methods: The study included 100 patients who had been previously treated with two or three daily doses of premix insulin.