Publications by authors named "Vanja Canovic"
Front Med (Lausanne)
December 2024
Article Synopsis
- ACE2 and TMPRSS2 are key genes that influence how SARS-CoV-2 enters cells, and their variations may impact COVID-19 severity and mortality.
- A study of 178 hospitalized COVID-19 patients in Serbia collected genetic data and found specific polymorphisms (rs2070788 and rs2106809) linked to reduced severity and death risk in females.
- The study concludes that these genetic variations could serve as important predictors for how severe COVID-19 can become in women.
Leg Med (Tokyo)
March 2024
Article Synopsis
- - The study compared the effects of storing six different healthy tissue types (brain, heart, lung, liver, spleen, and kidney) at two different temperatures (-20 °C and -150 °C) for three months on tissue histomorphology and DNA quality.
- - Results showed that tissue stored at -150 °C experienced higher levels of histomorphological damage, while tissues at -20 °C maintained better structure and had higher DNA concentration, particularly in liver samples.
- - The findings suggest that storing tissues at -20 °C is just as effective, if not better, for preserving DNA quality and histomorphology compared to the ultra-cold -150 °C storage method.
Forensic Sci Med Pathol
January 2024
Article Synopsis
- * A study analyzed various volumes of VH from 66 cadavers collected 24-48 hours after death to assess DNA yield and purity using phenol‒chloroform‒isoamyl alcohol (PCI).
- * Results indicated that DNA extracted from VH is reliable for analysis, with concentrations ranging from 6.20 to 609.5 ng/µl and can be stored for up to 6 months without significant degradation.
