Publications by authors named "Vanina de Larouziere"

Article Synopsis
  • The study examines the role of the testicular isoform of angiotensin converting enzyme (tACE) in male fertility, particularly its impact on sperm binding to the zona pellucida (ZP) during fertilization, drawing parallels to findings in mice.
  • In the study, 24 men with similar normal semen parameters were analyzed, with 10 experiencing IVF failures and no sperm binding to the ZP, while 14 had successful fertilization.
  • Results revealed that 3 of the unsuccessful cases and 1 control had no tACE expression, but no genetic mutations were found, indicating that tACE does not play a significant role in human fertilization or ZP binding.
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Objective: To raise the possibility that pregnancy can be obtained by assisted reproductive techniques in patients with human seminal plasma allergy.

Design: Case report.

Setting: University hospital.

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We used the cumulative summation test for learning curve (LC-CUSUM), a specifically designed statistical tool, to evaluate the first 50 procedures performed by a trainee in vitrification and to provide a usable model for monitoring the learning process of this technique. Given the lack of models to evaluate IVF technologies, the CUSUM methodology could prove useful for quality control in laboratories.

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Background: Recent progress in the treatment of sickle cell disease, in particular the use of hydroxyurea, has considerably modified the prognosis of this disease. Many more patients now reach reproductive age. The objective of this study was to assess the potential impact of hydroxyurea on the semen of patients.

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