Spectroscopic and structural studies on phenyl and pentafluorophenyl trifluorothioacetate, and pentafluorophenyl trifluoroacetate, CFC(O)SCH, CFC(O)SCF and CFC(O)OCF.

Phenyl and pentafluorophenyl trifluorothioacetate, CFC(O)SCH and CFC(O)SCF, were prepared by condensation of CFC(O)Cl and the corresponding mercaptan RSH under vacuum conditions. The compounds were isolated and properly characterized by using infrared spectroscopy, UV-Vis, multinuclear NMR spectroscopy techniques and by mass spectrometry. The crystal structures have been determined for both CFC(O)SCH and according to the best of our knowledge the not yet reported in the literature CFC(O)SCF species.

Electrochemically addressed FET-like nanofluidic channels with dynamic ion-transport regimes.

Nanofluidic channels in which the ionic transport can be modulated by the application of an external voltage to the nanochannel walls have been described as nanofluidic field effect transistors (nFETs) because of their analogy with electrolyte-gated field effect transistors. The creation of nFETs is attracting increasing attention due to the possibility of controlling ion transport by using an external voltage as a non-invasive stimulus. In this work, we show that it is possible to extend the actuation range of nFETs by using the supporting electrolyte as a "chemical effector".

Highly sensitive acetylcholine biosensing chemical amplification of enzymatic processes in nanochannels.

Acetylcholinesterase-modified nanochannels are proposed as reliable and reproducible nanofluidic sensors for highly sensitive detection of acetylcholine. The operation mechanism relies on the use of weak polyelectrolytes as "chemical amplifiers" that adjust/reconfigure the nanochannel surface charge in the presence of local pH changes induced by the enzymatic reaction. Experimental results show that the presence of acetylcholine can be transduced into measurable ionic signals with a low limit of detection.

Borate-driven ionic rectifiers based on sugar-bearing single nanochannels.

Recently, much scientific effort has been centered on the control of the ionic transport properties of solid state nanochannels and the rational design and integration of chemical systems to induce changes in the ionic transport by means of interactions with selected target molecules. Here, we report the fabrication of a novel nanofluidic device based on solid-state nanochannels, which combines silane chemistry with both track-etched and atomic layer deposition (ALD) technologies. Nanodevice construction involves the coating of bullet-shaped single-pore nanochannels with silica (SiO) by ALD and subsequent surface modification by reaction between silanol groups exposed on pore walls and N-(3-triethoxysilylpropyl)-gluconamide, in order to create a gluconamide-decorated nanochannel surface.

High-sensitivity detection of dopamine by biomimetic nanofluidic diodes derivatized with poly(3-aminobenzylamine).

During the last few years, much scientific effort has been devoted to the control of ionic transport properties of solid state nanochannels and the rational integration of chemical systems to induce changes in the ionic transport by interaction with selected target molecules for (bio)sensing purposes. In this work, we present the construction and functional evaluation of a highly sensitive dopamine-responsive iontronic device by functionalization of bullet-shaped track-etched single nanochannels in PET membranes with poly(3-aminobenzylamine) (PABA). The variety of basic groups in this amino-appended polyaniline derivative allows programming of the ion selectivity of the channel by setting the pH conditions.

Electrochemically addressable nanofluidic devices based on PET nanochannels modified with electropolymerized poly-o-aminophenol films.

Nanofluidic field-effect transistors (nFETs) have attracted attention from the scientific community due to their remarkable level of control over ionic transport. Particularly, the combination of nanofluidic systems and electroactive polymers has demonstrated to be an interesting approach to achieve an electrochemically addressable device. In this work, the development of nFETs based on the integration of electropolymerized poly-o-aminophenol (POAP) films into track-etched nanochannels is proposed.