Biosorption and Symbiotic Potential of Horse Gram Rhizobia in Soils Contaminated with Cobalt.

The current study aims evaluation of biosorption and symbiotic potential of horse gram plants associated with rhizobia inspite of Cobalt (Co) metal stress, and these rhizobia strains play a pivotal role in the phytoremediation of Co heavy metal-contaminated soils. Horse gram rhizobial isolates HGR-4, HGR-6, HGR-13 and HGR-25 were able to tolerate 1000 µg g Co supplemented in culture media and also 100 µg g in Co supplemented soil. The plants nodulated with the isolates from the study have shown higher nodulation, nitrogen and leghaemoglobin content in the potted experiment on par with the control plants.

Nickel tolerance and biosorption potential of rhizobia associated with horse gram [ (Lam.) Verdc.].

The rhizobia isolated from root nodules of horse gram were screened for nickel (Ni) tolerance . The strain HGR-4 could tolerate 1000 µg g of Ni. It was also observed that horse gram plants associated with HGR-4 have shown Ni stress tolerance in Ni amended soils up to a concentration of 100 µg g.

Synthesis, Screening and Docking Analysis of Hispolon Pyrazoles and Isoxazoles as Potential Antitubercular Agents.

Background: Hispolons are natural products known to possess cytoprotective, antioxidant and anti-cancer activities. We have found recently anti TB activity in these compounds. Efforts were made to optimize the structure with bioisosteric replacement of 1,3-diketo functional group with the corresponding pyrazole and isoxazole moieties.