Wnt3a but not CDX-2 expression is associated with differentiated thyroid cancer.

Objective: Thyroid neoplasm incidence has increased worldwide, mostly due to the advancements in medical imaging and screening rates. The aberrant Wnt/β-catenin pathway has been identified as a key mechanism, and it has also been related to the metastatic activity of differentiated thyroid cancer. We aimed to verify the difference in the expression of Wnt3a, a canonical activator of the β-catenin signaling, and CDX-2, a transcription factor upregulated by Wnt/β-catenin pathway, in multinodular goiter and differentiated thyroid cancer and to determine their prognostic value.

Assessment of noise level and risk of hearing loss among musicians.

Introduction: music is performed with specific drums, which produce loud and low-tone sounds that can potentially lead to hearing risk.

Objectives: To assess sound pressure levels and hearing safety of musicians who play in groups.

Methods: Using a decibel meter, noise exposure was measured in two different groups (group 1 and group 2), which are divided into categories: (group 1 = five categories - junior, free, general a, general b, and master, and group 2 = two categories - adult and child).