Publications by authors named "Vanessa S Fortes"

Article Synopsis
  • The study aimed to profile individuals who initiated HIV post-exposure prophylaxis (PEP) in Brazil, focusing on key populations as per the Brazilian Ministry of Health's recommendations.
  • Data was collected retrospectively from 2015-2018, revealing that most users were young males, predominantly white, well-educated, and had multiple sexual partners, with a notable presence of substance use in this group.
  • Findings highlighted disparities in PEP usage among vulnerable groups, showing significantly lower participation rates among transgender individuals and sex workers compared to other populations.
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The process of soybean biotransformation increases the quantity of isoflavones (daidzein and genistein), which besides being considered an alternative to estroprogestive hormone replacement therapy (HRT), are able of hindering the growth and development of tumor cells. We investigated the effects of soybean extract biotransformed by fungus on estrogen-dependent (MCF-7) and nondependent (SK-BR-3) breast cell lines. Cells were treated with different concentrations of biotransformed (BSE) and nonbiotransformed soybean extract (SE), or daidzein (D) and genistein (G) patterns isolated and in combination (D + G).

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Exposure to solar radiation, particularly its ultraviolet (UV) component, has a variety of harmful effects on human health. Some of these effects include sunburn cell formations, basal and squamous cell cancers, melanoma, cataracts, photoaging of the skin, and immune suppression. The beneficial photoprotective effects of topical formulations with the extract, Morinda citrifolia, have not been investigated.

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Melanoma is recognized as one of the most aggressive cancers with a relatively high propensity for metastasis. The prognosis of melanoma remains poor in spite of treatment advances, emphasizing the importance of additional preventive measures. Isoflavonoids have become not only potential chemopreventive, but also important therapeutic natural agents.

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Vulvovaginal candidiasis is the second cause of vaginal infection in the USA. Clinical treatment of C. albicans infections is routinely performed with polyenes and azole derivatives.

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