Publications by authors named "Vanessa Reyes"
Article Synopsis
- Dopamine neurons in the ventral tegmental area play a key role in intracranial self-stimulation (ICSS), but their exact cognitive functions are still not fully understood.
- 20-Hz stimulation of dopamine neurons mimics a weak prediction error and fails to support ICSS beyond a simple reinforcement schedule, lacking the ability to assign value to cues.
- In contrast, 50-Hz stimulation significantly enhances ICSS, providing a specific reward representation that motivates behavior, indicating that the frequency of stimulation affects dopamine release modulations.
The small monomeric GTPase RHOA acts as a master regulator of signal transduction cascades by activating effectors of cellular signaling, including the Rho-associated protein kinases ROCK1/2. Previous in vitro cell culture studies suggest that RHOA can regulate many critical aspects of vascular endothelial cell (EC) biology, including focal adhesion, stress fiber formation, and angiogenesis. However, the specific in vivo roles of RHOA during vascular development and homeostasis are still not well understood.
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