Publications by authors named "Vanessa Pleguezuelos"
Background: Human milk is the best option for feeding newborns, especially premature infants. In the absence of breast milk, milk from a human milk bank can be a suitable alternative. However, the nutritional content of human milk may be insufficient to meet these high requirements and milk fortification is needed.
View Article and Find Full Text PDFBackground: Ambient air pollution has been associated with COVID-19 disease severity and antibody response induced by infection.
Objectives: We examined the association between long-term exposure to air pollution and vaccine-induced antibody response.
Methods: This study was nested in an ongoing population-based cohort, COVICAT, the GCAT-Genomes for Life cohort, in Catalonia, Spain, with multiple follow-ups.
Article Synopsis
- The study examines the antibody responses to SARS-CoV-2 among 1,076 adults in Catalonia, measuring IgM, IgA, and IgG levels before and after vaccination between June 2020 and July 2021.
- Key findings show that 35.8% of unvaccinated, previously infected individuals experienced antibody decline, with age, asymptomatic infections, and smoking as contributing factors; vaccinated individuals had higher antibody levels and a recorded increase in responses after the second vaccine dose.
- Vaccination significantly boosts immune responses, especially evident in those previously infected, with different mRNA vaccines showing varied effectiveness in generating antibody levels post-vaccination.
Background: Emerging evidence links ambient air pollution with coronavirus 2019 (COVID-19) disease, an association that is methodologically challenging to investigate.
Objectives: We examined the association between long-term exposure to air pollution with SARS-CoV-2 infection measured through antibody response, level of antibody response among those infected, and COVID-19 disease.
Methods: We contacted 9,605 adult participants from a population-based cohort study in Catalonia between June and November 2020; most participants were between 40 and 65 years of age.
Sparse data exist on the complex natural immunity to SARS-CoV-2 at the population level. We applied a well-validated multiplex serology test in 5000 participants of a general population study in Catalonia in blood samples collected from end June to mid November 2020. Based on responses to fifteen isotype-antigen combinations, we detected a seroprevalence of 18.
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