Publications by authors named "Vanessa Mba Matah Marthe"

Objectives: This work was carried out with a view to determining the antioxidant, anti-inflammatory and anti-ulcer properties of the aqueous lyophilized extract of .

Methods: proteinases inhibition, albumin denaturation, hemolysis of red blood cells by heat, inhibition of the proton pump H/KATPase, FRAP (Ferric reducing antioxidant power) and DPPH (1,1-diphenyl-2-picrylhydrazyl) assays were performed. , cold water immersion-induced ulceration and methylene blue-induced ulceration was used to determine the anti-ulcer properties of the lyophilizate (100, 200 and 300 mg/kg).

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Objectives: In this study, we determined the gastroprotective and ulcer-healing effects of extracts (aqueous and methanolic) of stem-back.

Methods: Gastroprotective and healing activity were evaluated following a HCl/ethanol and an indomethacin-induced acute ulcers models; acetic acid, pylorus-ligature, pylorus ligature/histamine and pylorus ligature/acetylcholine-induced chronic ulcers models.

Results: It emerges from this study that, at 100, 200 and 400 mg/kg, the extracts significantly reduced the various ulceration parameters.

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Objectives: (, Bignoniaceae) is mainly found in tropical/neotropical regions of America, Africa and Asia. The plant's leaves, stems or roots are used to treat anaemia, bloody diarrhoea, parasitic and microbial infections. This study evaluates anti-inflammatory properties () of and their curative effects on paclitaxel-induced intestinal toxicity ().

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In traditional Cameroonian medicine, to relieve many inflammations, parts of , are very widely used. This study considered the evaluation of acute toxicity and anti-inflammatory properties of the hydroethanolic extract of the roots of . In an acute toxicity study, 250, 2500, and 5000 mg/kg were administered orally to mice in a single dose, and general behavior, adverse effects, and mortality were monitored.

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An ulcer is an erosion of the gastric mucosa that occurs following an imbalance between the aggression and protective factors and/or an infection with (). About 90-100% of duodenal ulcers and 70-80% of gastric ulcers are caused by . The objective of this work was to evaluate in the anti- activity and then the anti-inflammatory and antioxidant properties of aqueous and methanol extracts of .

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Objectives: In African traditional medicine, (Caesalpiniaceae) is used to treat many diseases including gastric ulcers. We evaluated in this study, the cytoprotective and antisecretory properties of the methanolic extract of the stem bark of this plant using different technics of gastric lesion induction.

Methods: Cytoprotective and antisecretory activity of the methanolic extract of stem bark was evolved through six methods of gastric lesion induction in experimental male rats (150-200 g): (1) gastric lesions induced by HCl/ethanol, (2) gastric lesions induced by Indomethacin- HCl/ethanol, (3) gastric lesion induced by Indomethacin, (4) gastric lesions induced by Pylorus ligation, (5) gastric lesions induced by histamine-Pylorus ligation, (6) gastric lesions induced by carbachol-Pylorus ligation.

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