Publications by authors named "Vanessa M B da Fonseca"
Objective: The authors hypothesized that ventilation and hyperoxia may harm the cochlea vasculature in an experimental model of Congenital Diaphragmatic Hernia (CDH) performed in rabbits.
Methods: New Zealand rabbits underwent CDH creation at 25 days of gestation (term = 30 days). CDH was created in fetuses (n = 15) and compared with Controls (n = 15).
The Effect of Lacticaseibacillus rhamnosus, Lacticaseibacillus paracasei, and Bifidobacterium animalis ssp. lactis on the Prevention of Asthma in an Animal Model.
Líris Marini Dias Coelho Vanessa Maciel Braulio da Fonseca Ivana Golçalves Labadessa Sergio Luiz Salvador Marina Del Arco Mastrange
Probiotics Antimicrob Proteins
October 2024
Article Synopsis
- The rise in asthma cases, especially in urban areas, has led to research on preventive measures, driven by the hygiene theory which suggests early exposure to infections may protect against allergic diseases.
- The study evaluated the effects of three specific probiotics (Lacticaseibacillus rhamnosus, Lacticaseibacillus paracasei, and Bifidobacterium animalis ssp. lactis) on asthma using mice, testing different concentrations over 26 days prior to allergen exposure.
- Results showed that none of the probiotics effectively reduced asthma-related symptoms like airway inflammation and bronchial hyperresponsiveness, indicating that the effectiveness of probiotics varies by strain and dosage, prompting the need for further research.
L. improves airway hyperresponsiveness and suppresses inflammation in a murine model of allergic asthma.
Clara do Prado Lopes Frota Alessa Castro Ribeiro Marco Túlio Alvarenga Calil Filho Lucas Junqueira de Freitas Morel Leandra Naira Zambelli Ramalho Vanessa Maciel Braulio da Fonseca
Allergol Immunopathol (Madr)
April 2022
Objective: To evaluate the effect of a hydroethanolic extract of L. ("bitter melon", Cucurbitaceae) leaves (MCHA) on ovalbumin (OVA)-induced asthma model. Balb/c mice were sensitized twice and challenged for 4 alternate days with OVA and then treated with MCHA (500 mg/kg) for 7 consecutive days.
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