Variations of plasma leptin and adiponectin levels in autistic patients.

Autism is a neurodevelopmental disorder with pathogenesis not completely understood. Although a genetic origin has been recognized, it has been hypothesized a role for environmental factors, immune dysfunctions, and alterations of neurotransmitter systems. In young autistic patients we investigated plasma leptin and adiponectin levels over a year period.

EEG features and epilepsy in MECP2-mutated patients with the Zappella variant of Rett syndrome.

Objective: To assess the presence/absence of peculiar EEG features and epilepsy in MECP2-mutated Rett patients with the Zappella-Rett variant (Z-RTT) also known as preserved speech variant.

Methods: Retrospective analysis of 16 (age 19.4+/-8.