Publications by authors named "Vanessa Garnier"
Article Synopsis
- - Pregnancy-induced hypertension diseases include gestational hypertension, preeclampsia, and eclampsia, and their mechanisms are not fully understood.
- - The study investigates the role of endocrine gland-derived vascular endothelial growth factor (EG-VEGF), which is secreted by the placenta and may contribute to pregnancy-induced hypertension if its levels remain elevated beyond the first trimester.
- - Experiments in mice showed that increased EG-VEGF resulted in poor placental function, increased hypoxia, and ultimately led to gestational hypertension and kidney dysfunction, highlighting EG-VEGF's pivotal role in these pregnancy complications.
PPARγ-deficient mice die at E9.5 due to placental abnormalities. The mechanism by which this occurs is unknown.
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