Publications by authors named "Vanessa Freire"
In recent years, the Zika Virus (ZIKV) has caused pandemic outbreaks associated with a high rate of congenital ZIKV syndrome (CZS). Although all strains associated with worldwide outbreaks derive from the Asian lineage, the reasons for their enhanced spread and severity are not fully understood. In this study, we conducted a comparative analysis of miRNAs (miRNA-155/146a/124) and their cellular targets (SOCS1/3, SHP1, TRAF6, IRAK1), as well as pro- and anti-inflammatory and anti-viral cytokines (IL-6, TNF-α, IFN-γ, IL-10, and IFN-β) and peroxisome proliferator-activated receptor γ (PPAR-γ) expression in BV2 microglia cells infected with ZIKV strains derived from African and Asian lineages (ZIKV and ZIKV).
View Article and Find Full Text PDFObjectives: to create a software application for nursing education on child development assessment.
Methods: this is a methodological applied research developed in three stages: analysis, design, and development. Product quality characteristics from the ISO/IEC 25010 standards were adopted.
Objective: To analyze the relevance of clinical indicators and the clarity and precision of conceptual and operational definitions of the diagnosis Impaired gas exchange.
Methods: Content analysis, by 39 nurse judges, divided into the phases of conceptual definition of the phenomenon of interest, construction of the structure of the phenomenon of interest and analysis of the judges on the built structure.
Results: From the 22 indicators, 21 were considered relevant Impaired gas exchange.
The purpose of this study was to evaluate the impact of implementing a care bundle for preventing peri-intraventricular hemorrhage (PIVH) in preterm newborns. A longitudinal, quantitative, quasi-experimental study was conducted with preterm newborns from a neonatal unit. The study was divided into 2 stages: the first consisted of a retrospective cohort of newborns (control group) not exposed to the bundle, and the second consisted of 5 practical steps of implementing a care bundle for preventing PIVH in eligible newborns.
View Article and Find Full Text PDFObjective: to evaluate functional performance and technical quality of user embracement software with pediatric risk classification.
Method: descriptive exploratory study developed based on the quality requirements set forth in ISO/IEC 25010. The evaluated characteristics were: functional adequacy, reliability, usability, performance efficiency, compatibility, safety, maintainability and portability.
Background: It is undeniable that diabetes may cause several health complications for the population. Many of these complications are associated with poor glycemic control. Due to this, strategies to handle this problem are of great clinical importance and may contribute to reducing the various complications from diabetes.
View Article and Find Full Text PDFBackground: Surgical recovery can be defined as the days required to initiate activities that maintain life, health, and well-being.
Aim: The main study objective was to compare the effectiveness of telephone versus conventional follow-up in postsurgical older adult patients.
Methods: This is a quasi-experimental study with random sampling.
Objective: To evaluate the efficacy of topically applied autologous plasma rich in growth factors (PRGF) as a treatment for persistent epithelial defects (PEDs) of the cornea.
Methods: A series of prospective noncomparative cases.
Participants: Twenty eyes from 18 patients with PED with various underlying etiopathologies: neurogenic, iatrogenic, associated with burning or secondary to severe dry eye.