Publications by authors named "Vanessa Figueiredo Monteleone"
Am J Med Genet A
February 2022
Article Synopsis
- - Williams-Beuren syndrome (WBS) is a rare genetic disorder marked by facial features, intellectual disability, a friendly demeanor, and significant cardiovascular issues, particularly supravalvular aortic stenosis (SVAS).
- - A study of 127 WBS patients over 20 years found that 74% had cardiovascular defects, with nearly one-quarter requiring surgical procedures, including one case of heart transplantation due to severe heart failure.
- - Cardiovascular complications are a leading cause of mortality in WBS patients, highlighting the importance of careful surgical planning, monitoring, and multidisciplinary care for those requiring heart surgeries.
