Publications by authors named "Vanessa F Franco"

Article Synopsis
  • - Cervical cancer is a leading cancer in women, mainly linked to HPV types 16 and 18, with a significant part of cases showing genetic diversity that may influence cancer progression.
  • - This study analyzed HPV16 and HPV18 genetic variations in 594 Brazilian women with invasive cervical cancer, identifying prevalent lineages before Brazil's public immunization program.
  • - Findings revealed that lineage A was most common for both HPV16 (in 217 women) and HPV18 (in 56 women), with HPV16 showing signs of recent variant expansion associated with cancer, unlike HPV18.
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Ovarian carcinoma is one of the most aggressive gynecological diseases and generally diagnosed at advanced stages. Osteopontin (OPN) is one of the proteins overexpressed in ovarian cancer and is involved in tumorigenesis and metastasis. Alternative splicing of OPN leads to 3 isoforms, OPNa, OPNb, and OPNc.

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