Publications by authors named "Vanessa Cristine de Souza Carneiro"
Herpesvirus is associated with various neurological disorders and a specific diagnosis is associated with a better prognosis. MicroRNAs (miRNAs) are potential diagnostic and prognostic biomarkers of neurological diseases triggered by herpetic infection. In this review, we discuss miRNAs that have been associated with neurological disorders related to the action of herpesviruses.
View Article and Find Full Text PDFHuman herpesviruses (HHVs) can establish latency and be reactivated, also are neurotropic viruses that can trigger neurological disorders. HHV-6 is a herpesvirus that is associated with neurological disorders. Studies have reported the detection of HHV-6 in patients with COVID-19 and neurological manifestations.
View Article and Find Full Text PDFClinical Profile and Risk Factors for Severe COVID-19 in Hospitalized Patients from Rio de Janeiro, Brazil: Comparison between the First and Second Pandemic Waves.
J Clin Med
March 2023
Article Synopsis
- Brazil has faced significant challenges during the COVID-19 pandemic, particularly with the emergence of a new variant that sparked a second wave of infections.
- A study analyzed critically ill patients in Rio de Janeiro, revealing that a high percentage had comorbidities, and severe disease was linked to older age and various medical conditions.
- Findings indicated an increase in the need for invasive respiratory support and acute hepatitis during the second wave, underscoring the importance of this research for improving clinical care and public health strategies.
This article addresses the relationship between human herpesviruses (HHVs) and neuroinfections. Alphaherpesviruses, betaherpesviruses and gammaherpesviruses are neurotropic viruses that establish latency and exhibit reactivation capacity. Encephalitis and meningitis are common in cases of HHV.
View Article and Find Full Text PDFArticle Synopsis
- A study investigated the prevalence of herpesvirus in 53 COVID-19 patients, revealing that 79.2% had at least one type of herpesvirus, with HHV-6, cytomegalovirus, and HHV-7 being the most common.
- The research found a significant correlation between high SARS-CoV-2 viral loads and the presence of herpes simplex virus 1, and 26.4% of patients with coinfections exhibited neurological symptoms.
- Although coinfection did not result in worse overall outcomes, there was a noteworthy association between HHV-6 detection and neurological changes in patients.
Validation of a novel molecular assay to the diagnostic of COVID-19 based on real time PCR with high resolution melting.
PLoS One
December 2021
The emergence of the COVID-19 pandemic resulted in an unprecedented need for RT-qPCR-based molecular diagnostic testing, placing a strain on the supply chain and the availability of commercially available PCR testing kits and reagents. The effect of limited molecular diagnostics-related supplies has been felt across the globe, disproportionally impacting molecular diagnostic testing in developing countries where acquisition of supplies is limited due to availability. The increasing global demand for commercial molecular diagnostic testing kits and reagents has made standard PCR assays cost prohibitive, resulting in the development of alternative approaches to detect SARS-CoV-2 in clinical specimens, circumventing the need for commercial diagnostic testing kits while mitigating the high-demand for molecular diagnostics testing.
View Article and Find Full Text PDFIntroduction: Despite their widespread usage, synthetic insecticides and larvicides are harmful for controlling disease-causing mosquitoes owing to the development of resistance. The leaves of Eugenia astringens, Myrrhinium atropurpureum, and Neomitranthes obscura were collected from Marambaia and Grumari restingas. The safety and larvicidal efficacy of their extracts were tested against Aedes (Stegomyia) aegypti L.
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